文献类型：期刊文献

英文题名：Cascade Radical Annulation of 2-Alkynylthio(seleno)anisoles with Acetone or Acetonitrile: Synthesis of 3-Acetomethyl- or Cyanomethyl-Substituted Benzothio(seleno)phenes

作者：Cai, Tao[1];Shen, Fangqi[2];Ni, Yuqi[1];Xu, Huiting[1];Shen, Runpu[1];Gao, Yuzhen[3]

机构：[1]Shaoxing Univ, Coll Chem & Chem Engn, Shaoxing 312000, Peoples R China;[2]Northwest Normal Univ, Coll Chem & Chem Engn, Lanzhou 730070, Peoples R China;[3]Chinese Acad Sci, Fujian Inst Res Struct Matter, Key Lab Coal Ethylene Glycol & Its Related Techno, Fuzhou 350002, Peoples R China

年份：2021

卷号：86

期号：1

起止页码：1002

外文期刊名：JOURNAL OF ORGANIC CHEMISTRY

收录：SCI-EXPANDED(收录号：WOS:000606840200082)、、EI(收录号：20205109658273)、Scopus(收录号：2-s2.0-85097743240)、WOS、CCR-EXPANDED(收录号：WOS:000606840200082)

基金：Gao gratefully thanks the Natural Science Foundation of China (grant no. 21801240). Also, Cai gratefully thanks the Zhejiang Provincial Natural Science Foundation of China (grant no. LQ21B020005) and the Youth Fund of Shaoxing University (no. 20185019).

语种：英文

外文关键词：Acetone - Acetonitrile

外文摘要：An efficient method for the direct preparation of 3-aceto(cyano)methyl-substituted benzothio(seleno)phenes has been achieved through C(sp(3))-H bond activation of easily available acetone or acetonitrile and cascade radical cyclization reaction. In this cascade radical cyclization reaction, C(sp(2))-C(sp(3)) and C(sp(2))-S bonds, as well as benzenethio(seleno)phene skeletons, can be built along with the cleavage of the C(sp(3))-S bond, demonstrating the high step-economics and efficiency of this approach.