文献类型：期刊文献

英文题名：Efficacy of Cognitive Behavioral Therapy on Mood Disorders, Sleep, Fatigue, and Quality of Life in Parkinson's Disease: A Systematic Review and Meta-Analysis

作者：Luo, Fangyi[1,2];Ye, Mengfei[1];Lv, Tingting[2];Hu, Baiqi[3];Chen, Jiaqi[2];Yan, Junwei[2];Wang, Anzhe[2];Chen, Feng[2];He, Ziyi[2];Ding, Zhinan[4];Zhang, Jian[2];Qian, Chao[1];Liu, Zheng[2,4]

机构：[1]Shaoxing Univ, Shaoxing Peoples Hosp 7, Affiliated Mental Hlth Ctr, Coll Med,Dept Psychiat, Shaoxing, Peoples R China;[2]Shaoxing Univ, Coll Med, Ctr Sci Res, Dept Behav Neurosci, Shaoxing, Peoples R China;[3]China Med Univ, Shaoxing Hosp, Dept Neurol, Shaoxing, Peoples R China;[4]Shaoxing Univ, Lab Forens Toxicol, Judicial Identificat Ctr, Shaoxing, Peoples R China

年份：2021

卷号：12

外文期刊名：FRONTIERS IN PSYCHIATRY

收录：SSCI(收录号：WOS:000736335900001)、SCI-EXPANDED(收录号：WOS:000736335900001)、、Scopus(收录号：2-s2.0-85121907015)、WOS

基金：This work was funded by Zhejiang Medical Health Science and Technology Project (Nos. 2019KY724 and 2020KY332), the Scientific Research Fund of Shaoxing University (No. 20125025), and the National Training Program of Innovation and Entrepreneurship for College Students (No. 2017R10349001).

语种：英文

外文关键词：cognitive behavioral therapy; Parkinson's disease; non-motor symptoms; quality of life; meta-analysis

外文摘要：Objective: The aim of this study was to perform a quantitative analysis to evaluate the efficacy of cognitive behavioral therapy (CBT) on mood disorders, sleep, fatigue, and its impact on quality of life (QOL) in Parkinson's Disease (PD).
Methods: We searched for randomized controlled trials in three electronic databases. Fourteen studies, including 507 patients with PD, met the inclusion criteria. We determined the pooled efficacy by standard mean differences and 95% confidence intervals, using I-2 to reveal heterogeneity.
Results: The result showed CBT had a significant effect on depression [-0.93 (95%CI, -1.19 to -0.67, P < 0.001)] and anxiety [-0.76 (95%CI, -0.97 to -0.55, P < 0.001)]. Moderate effect sizes were noted with sleep disorders [-0.45 (95% CI, -0.70 to -0.20, P = 0.0004)]. There was no evident impact of CBT on fatigue or QOL. We found an intervention period > 8 weeks was advantageous compared with < 8 weeks, and CBT implemented in non-group was more effective than in group. Between the delivery methods, no significant difference was found.
Conclusion: We found that CBT in patients with PD was an efficacious therapy for some non-motor symptoms in PD, but not efficacious for fatigue and QOL. These results suggest that CBT results in significant improvement in PD and should be used as a conventional clinical intervention.