文献类型：期刊文献

中文题名：Isolation and characterization of liver epithelial progenitor cells from normal adult rhesus monkeys （Macaca mulatta）

英文题名：Isolation and characterization of liver epithelial progenitor cells from normal adult rhesus monkeys （Macaca mulatta）

作者：Lifang Jin[1,2,3,4];Shaohui Ji[1,2,3];Xianghui Tang[1,3];Xiangyu Guo[1,2,3];Yongqing Lu[1,2,3];Hongwei Chen[1,2,3];Hongkui Deng[5];Qi Zhou[6];Weizhi Ji[1,3,7]

机构：[1]Kunming Primate Research Center, and Kunming Institute of Zoology, Chinese Academy of Scienees, Kunming, Yunnan, China;[2]Graduate School, Chinese Academy of Sciences, Beijing, China;[3]Yunnan Key Laboratory of Animal Reproductive Biology, Kunming, Yunnan, China;[4]College of Life Sciences, Shaoxing University, Zhejiang, China;[5]Key Laboratory of Cell Proliferation and Differentiation of the Ministry of Education, College of Life Sciences, Peking University, Beijing, China;[6]Institute of Zoology, Chinese Academy of Sciences, Beijing, China;[7]Kunming Biomed International

年份：2009

卷号：19

期号：2

起止页码：268

中文期刊名：细胞研究：英文版

外文期刊名：Cell Research

收录：CSTPCD、、Scopus、CSCD2011_2012、CSCD、PubMed

语种：英文

中文关键词：干细胞;细胞起源;HPCs;研究

外文摘要：Dear Editor, Based on their ability to proliferate and the capacity to differentiate into specific cell types, hepatic progenitor/stem cells （HPCs） from adult human liver may have potential therapeutic effects on end-stage liver failure. In addition, adult HPCs have a reduced risk of teratoma for- mation and are not subject to the same ethical issues as fetal HPCs or embryonic stem cells . The HPCs from rhesus monkeys are relevant because they may serve as a valuable preclinical model for assessment of cell therapy in humans. To date, there are no reports of HPCs or liver epithelial progenitor cells （LEPCs） isolated from normal adult rhesus monkey although a few studies in other species were reported. We report here for the first time the successful isolation of rhesus monkey LEPCs （mLEPCs） from normal adult livers （n = 12）.