文献类型：期刊文献

英文题名：Intermittent Theta Burst Stimulation vs. High-Frequency Repetitive Transcranial Magnetic Stimulation in the Treatment of Methamphetamine Patients

作者：Liu, Qingming[1,2,3];Sun, Huimeng[2];Hu, Yitian[2];Wang, Qiongyao[2];Zhao, Zhiyong[4];Dong, Da[1,2];Shen, Ying[5]

机构：[1]Shaoxing Univ, Ctr Brain Mind & Educ, Shaoxing, Peoples R China;[2]Shaoxing Univ, Sch Teacher Educ, Shaoxing, Peoples R China;[3]Nanjing Normal Univ, Sch Psychol, Nanjing, Peoples R China;[4]Zhejiang Univ, Coll Biomed Engn & Instrument Sci, Dept Biomed Engn, Key Lab Biomed Engn,Minist Educ, Hangzhou, Peoples R China;[5]Nanjing Med Univ, Rehabil Med Ctr, Affiliated Hosp 1, Nanjing, Peoples R China

年份：2022

卷号：13

外文期刊名：FRONTIERS IN PSYCHIATRY

收录：SSCI(收录号：WOS:000860833900001)、SCI-EXPANDED(收录号：WOS:000860833900001)、、Scopus(收录号：2-s2.0-85130863795)、WOS

基金：This work was supported by the National Social Science Fund of China (Grant No. 20CZX015) and the National Science Foundation of China (Grant No. 81702230).

语种：英文

外文关键词：methamphetamine use disorder; iTBS; rTMS; substance abuse; addiction

外文摘要：Background and Aims: In this brief report, we compare the effectiveness and safety of intermittent theta burst stimulation (iTBS) and conventional 10 Hz repetitive transcranial magnetic stimulation (rTMS) in patients with methamphetamine use disorder (MAUD). Our study suggests that iTBS would also reduce drug craving in patients with MAUD just as the 10 Hz; thus, there may be no difference in treatment effects between these two methods. Methods: In total twenty male methamphetamine (MA) addicts were randomly assigned to iTBS (n = 10) or 10 Hz (n = 10) groups for 12 treatments. Cue-evoked cravings, anxiety, depression, and withdrawal symptoms were measured at baseline before the first treatment, and post-tests after days 10, 15, and 20. Results: The results showed that iTBS and 10 Hz treatment had similar effectiveness in reducing cue-induced craving in male addicts for MA. Both 10 Hz and iTBS improved withdrawal symptoms of patients with MAUD. Conclusions: Intermittent theta burst stimulation may be similar in effectiveness as 10 Hz in treating patients with MAUD. The clinical usefulness of rTMS could be improved substantially because of the increase in its capacity, cost, and accessibility. Importantly, the effectiveness of rTMS in the treatment of patients with MAUD is not yet proven, and should be tested in the large double-blind sham-controlled studies.