文献类型：期刊文献

英文题名：The role of long noncoding ribonucleic acids in the central nervous system injury

作者：Huang, Min[1];Wang, Xizhi[1,2];Botchway, Benson O. A.[3];Zhang, Yong[1];Liu, Xuehong[1]

机构：[1]Shaoxing Univ, Sch Med, Dept Histol & Embryol, Shaoxing 312000, Peoples R China;[2]Ningbo Univ, Lihuili Hosp, Dept Cardiol, Ningbo, Peoples R China;[3]Bupa Cromwell Hosp, London, England

年份：2023

外文期刊名：MOLECULAR AND CELLULAR BIOCHEMISTRY

收录：SCI-EXPANDED(收录号：WOS:001093485600001)、、Scopus(收录号：2-s2.0-85174973438)、WOS

基金：None.

语种：英文

外文关键词：Central nervous system; Brain injury; Spinal cord injury; Long noncoding ribonucleic acid; Inflammation

外文摘要：Central nervous system (CNS) injury involves complex pathophysiological molecular mechanisms. Long noncoding ribonucleic acids (lncRNAs) are an important form of RNA that do not encode proteins but take part in the regulation of gene expression and various biological processes. Multitudinous studies have evidenced lncRNAs to have a significant role in the process of progression and recovery of various CNS injuries. Herein, we review the latest findings pertaining to the role of lncRNAs in CNS, both normal and diseased state. We aim to present a comprehensive clinical application prospect of lncRNAs in CNS, and thus, discuss potential strategies of lncRNAs in treating CNS injury.