文献类型：期刊文献

英文题名：Ag-Mediated Radical Cyclization of 2-Alkynylthio(seleno)anisoles: Direct Synthesis of 3-Phosphinoylbenzothio(seleno)phenes

作者：Cai, Tao[1];Liu, Jian[1];Zhang, Huimiao[1];Wang, Xiaolong[1];Feng, Jing[1];Shen, Runpu[1];Gao, Yuzhen[2]

机构：[1]Shaoxing Univ, Coll Chem & Chem Engn, Shaoxing 312000, Peoples R China;[2]Chinese Acad Sci, Fujian Inst Res Struct Matter, Key Lab Coal Ethylene Glycol & Its Related Techno, Fuzhou 350002, Fujian, Peoples R China

年份：2019

卷号：21

期号：12

起止页码：4605

外文期刊名：ORGANIC LETTERS

收录：SCI-EXPANDED(收录号：WOS:000473116000044)、、Scopus(收录号：2-s2.0-85066974512)、WOS、CCR-EXPANDED(收录号：WOS:000473116000044)

基金：We gratefully thank the financial support from NSFC (Grant No. 21801240). T.C. thanks the Youth Foud of Shaoxing University (No. 20185019). Y.G. also thanks the National Postdoctoral Program for Innovative Talents (No. BX201700244).

语种：英文

外文摘要：A new method for the direct synthesis of 3-phosphinoylbenzothio(seleno)phenes has been achieved through an Ag-mediated radical addition-cyclization of 2-alkynylthio(seleno)anisoles with secondary phosphine oxides in good yields under mild conditions. In this single reaction, benzenethiophene or benzeneselenophene skeleton, C(sp(2))-P and C(sp(2))-S bonds can be constructed with the cleavage of the C(sp(3))-S bond, highlighting the efficiency and step-economics of this protocol.