文献类型：期刊文献

英文题名：Palladium(II)-Catalyzed Regioselective Arylation of Naphthylamides with Aryl Iodides Utilizing a Quinolinamide Bidentate System

作者：Huang, Lehao[1];Li, Qian[1,2];Wang, Chen[1];Qi, Chenze[1]

机构：[1]Shaoxing Univ, Inst Appl Chem, Zhejiang Key Lab Alternat Technol Fine Chem Proc, Shaoxing 312000, Zhejiang, Peoples R China;[2]Ningbo Univ, Coll Mat Sci & Chem Engn, Ningbo 310014, Zhejiang, Peoples R China

年份：2013

卷号：78

期号：7

起止页码：3030

外文期刊名：JOURNAL OF ORGANIC CHEMISTRY

收录：SCI-EXPANDED(收录号：WOS:000317327800021)、、EI(收录号：20131516202970)、Scopus(收录号：2-s2.0-84875944939)、WOS、CCR-EXPANDED(收录号：WOS:000317327800021)

基金：Funding from NSFC (No. 21172149), the Science and Technology Department of Zhejiang Province, and the Foundation of Shaoxing University (2012LG1005) is greatly acknowledged.

语种：英文

外文关键词：Activation analysis - Amides - Aromatic compounds - Catalysis - Regioselectivity

外文摘要：A palladium(II)-catalyzed quinolinamide-directed 8-arylation of 1-naphthylamides with aryl iodides is reported. The bidentate directing group (quinolinamide) proved to be crucial for a highly regioselective transformation. In addition, the amide directing group can be easily hydrolyzed under basic conditions to offer a range of 8-aryl-1-naphthylamine derivatives. The theoretical calculations suggest that the C-H arylation reaction proceeds through a sequential C-H activation/oxidative addition pathway.