文献类型：期刊文献

英文题名：Computed Tomography for Detecting Patent Foramen Ovale: A Meta-Analysis

作者：Lou, Jingjing[1];Bao, Yaya[2];Lv, Tian[1];Yang, Yue[1,3]

机构：[1]Zhuji Peoples Hosp Zhejiang Prov, Dept Neurol, Zhuji, Peoples R China;[2]Shaoxing Univ, Med Coll, Dept Neurol, Shaoxing, Peoples R China;[3]Zhuji Peoples Hosp Zhejiang Prov, Dept Neurol, 9,Jianmin Rd Taozhu St, Zhuji 311800, Zhejiang, Peoples R China

年份：2022

卷号：25

期号：6

起止页码：E849

外文期刊名：HEART SURGERY FORUM

收录：SCI-EXPANDED(收录号：WOS:000910944400002)、、Scopus(收录号：2-s2.0-85145668683)、WOS

语种：英文

外文摘要：Objective: Patent foramen ovale (PFO) has been regarded as a potential source of cryptogenic stroke, which was con-ventionally detected by transesophageal echocardiography. Cardiac computed tomography (CCT) is a promising, non-invasive test for detection of PFO. We sought to conduct a meta-analysis to evaluate the diagnostic performance of CCT in detecting PFO.Methods: PubMed, ISI Web of Knowledge, Embase, Cochrane Library, and Wanfang from inception to June 2020 were searched for relevant studies comparing CCT and trans -esophageal echocardiography as the reference standard in detecting PFO. A bivariate model was used to pool sensitivity and specificity and to construct summary receiver operating characteristic (SROC) curves. Results: A total of seven studies with 483 patients were included in this meta-analysis. For the diagnosis of PFO, CCT had a mean sensitivity and specificity of 0.70 [95% CI:0.58, 0.79] and 0.97 [95% CI: 0.95, 0.99]. The SROC analysis showed an area under the curve of 0.97.Conclusion: CCT shows good diagnostic accuracy in detecting PFO with relatively high sensitivity and specificity. CCT could be considered a noninvasive alternative to trans -esophageal echocardiography for detecting PFO.