登录    注册    忘记密码

详细信息

人胎生长发育过程中Bcl-2/Bax蛋白在胃壁组织中的表达     被引量:1

Expression of Bcl-2/Bax protein during the development of human fetal stomach

文献类型:期刊文献

中文题名:人胎生长发育过程中Bcl-2/Bax蛋白在胃壁组织中的表达

英文题名:Expression of Bcl-2/Bax protein during the development of human fetal stomach

作者:张剑[1];刘学红[2]

机构:[1]绍兴文理学院医学院药理学研究室,绍兴312000;[2]绍兴文理学院医学院组织学与胚胎学教研室,绍兴312000

年份:2009

卷号:32

期号:4

起止页码:463

中文期刊名:解剖学杂志

外文期刊名:Chinese Journal of Anatomy

收录:CSTPCD、、CSCD2011_2012、北大核心2008、北大核心、CSCD

基金:浙江省自然科学基金资助项目(Y204364);浙江省教育厅资助项目(20061164)

语种:中文

中文关键词:胃;Bcl-2蛋白;Bax蛋白;人胎;免疫组织化学

外文关键词:stomach; Bcl-2 protein; Bax protein; human fetus; immunohistoehemistry

中文摘要:目的:探讨人胎胃发育过程中细胞增殖与凋亡的变化规律。方法:应用免疫组织化学ABC法检测人胎胃壁组织内Bcl-2/Bax蛋白的表达。结果:第9~15周人胎胃壁肌间神经丛和黏膜下层部分细胞呈Bcl-2蛋白阳性表达,胃上皮细胞中见少量Bcl-2蛋白表达;Bax蛋白在胃上皮细胞的胞质内呈阳性或弱阳性表达,在肌间神经丛和黏膜下层有少数细胞呈弱阳性表达。结论:Bcl-2/Bax与人胎胃的生长发育关系密切。

外文摘要:Objective: To explore the cell proliferation and apoptosis during the development of human fetal stomach. Methods: Bcl-2 and Bax protein expressions were tested in the stomach of human fetus by ABC the immunohistochemical method.Results: The positive expression of Bcl-2 protein in the interrnuscular nerve plexus and submucous layer, and some expressions of Bcl-2 protein in the epithelium in human fetal stomach were detected from the ninth to fifteenth week of fetal periods. Bax protein expression was positive or weakly positive in the epithelial cells, and was weakly positive for a few of cells in the intermuscular nerve plexus and submucous layer in the stomach of human fetus. Conclusion: Bcl-2 and Bax are closely related to the development of human fetal stomach.

参考文献:

正在载入数据...

版权所有©绍兴文理学院 重庆维普资讯有限公司 渝B2-20050021-8
渝公网安备 50019002500408号 违法和不良信息举报中心