文献类型：期刊文献

英文题名：Preparation of hydrophobic spray-coated spunlace nonwoven fabrics: Possessing the potential for anti-adhesive medical dressings

作者：Gu, Jiahua[1,2];Dai, Xinxin[1,2];Liu, Shiyi[3];Zhang, Xiantao[4];Hu, Yinsong[5];Zhang, Yinjiang[1,2];Zou, Zhuanyong[1,2]

机构：[1]Shaoxing Univ, Key Lab Clean Dyeing & Finishing Technol Zhejiang, Shaoxing 312000, Zhejiang, Peoples R China;[2]Shaoxing Univ, Shaoxing Key Lab High Performance Fibers & Prod, Shaoxing 312000, Zhejiang, Peoples R China;[3]Shaoxing Fuqing Hlth Prod Co LTD, Shaoxing 312000, Zhejiang, Peoples R China;[4]Zhende Med Supplies Co L, Sch Med, Shaoxing 312000, Zhejiang, Peoples R China;[5]Zhejiang Baoren Hezhong Technol Co LTD, Shaoxing 312000, Zhejiang, Peoples R China

年份：2024

卷号：49

外文期刊名：SURFACES AND INTERFACES

收录：SCI-EXPANDED(收录号：WOS:001235418300001)、、Scopus(收录号：2-s2.0-85191350646)、WOS

基金：The research was financially supported by the National Natural Science Foundation of China Youth Found (program no. 51903156) , the Zhejiang Provincial science and technology Department research and development project (program no. 2022C01SA691301) , the National Innovation and Entrepreneurship Training Program of College Students (program no. 202210349056S and 202310349040) and the Science and Technology Guiding Project of China National Textile Industry Council (program no. 2022027) , The Joint Research Program of Shaoxing University and Shaoxing Institute, Zhejiang University (2023LHLG008) .

语种：英文

外文关键词：Anti-adhesion dressing; Cotton spunlace nonwoven fabric; Hydrophobic modification; Abrasion resistance; Peeling energy; Biocompatibility

外文摘要：Traditional dressings tend to adhere to wounds during the healing process, causing secondary damage and delaying wound healing during replacement. Hydrophobic surfaces are resistant to the adhesion of cellular and proteinaceous wound exudates. Herein, a hydrophobic spunlace nonwoven-based dressing composed of the nano-silica/polydimethylsiloxane (SiO 2 /PDMS) composite cotton mesh was developed by a two-step spraying method. The process parameters were optimized by the L 9 (3 4 ) orthogonal experiment to obtain fabrics with excellent hydrophobicity and abrasion resistance. The optimized fabric finishing effect was achieved when the SiO 2 concentration was 0.8 wt%, the PDMS concentration was 0.8 wt%, the heat treatment temperature was 130 degrees C, and the time was 12 h. After optimization, the contact angle (CA) of the fabric was 145.0 +/- 0.7 degrees , and it only dropped by about 1 degrees after the friction test. FTIR, XPS, SEM, and EDS analyses collectively demonstrated the presence of a cladding structure comprising SiO 2 and PDMS on the surface of the optimized fabric. This structural modification imparts desirable mechanical properties and anti-adhesion properties to the fabric. Tensile tests revealed little effect of the optimized finishing on the mechanical properties of the fabrics. Additionally, the antiadhesion properties of the fabrics were evaluated by an in vitro gelatin model, showing a significant reduction in peeling energy for the optimized fabric. The peeling energies of the optimized fabric were 43.1 +/- 28.8 J/m 2 and 84.1 +/- 12.6 J/m 2 in the machine direction (MD) and cross direction (CD), respectively, indicating about 80 % superior anti-adhesion effect compared to commercially available oil gauze. Furthermore, the optimized fabric exhibited excellent biocompatibility, causing no hemolysis, pro -coagulant effect and favorable cytocompatibility. These results indicate that this hydrophobic spunlace nonwoven fabric has great potential for the application of anti-adhesive medical dressings.