文献类型：期刊文献

英文题名：Feasibility of endoscopic resection without laparoscopic assistance for giant gastric subepithelial tumors originating from the muscularis propria layer (with video)

作者：Zhang, Yu[1,2,3];Meng, Qian[3];Zhou, Xian-Bin[1,2];Chen, Guang[4];Zhu, Lin-Hong[5];Mao, Xin-Li[1,2,3];Ye, Li-Ping[1,2]

机构：[1]Wenzhou Med Univ, Taizhou Hosp Zhejiang Prov, Dept Gastroenterol, 150 Ximen St, Linhai, Zhejiang, Peoples R China;[2]Key Lab Minimally Invas Tech & Rapid Rehabil Dige, 150 Ximen St, Linhai, Zhejiang, Peoples R China;[3]Shaoxing Univ, Sch Med, Shaoxing, Zhejiang, Peoples R China;[4]Wenzhou Med Univ, Taizhou Hosp Zhejiang Prov, Dept Gen Surg, Linhai, Peoples R China;[5]Wenzhou Med Univ, Taizhou Hosp Zhejiang Prov, Dept Med Adm, Linhai, Peoples R China

年份：2022

卷号：36

期号：5

起止页码：3619

外文期刊名：SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES

收录：SCI-EXPANDED(收录号：WOS:000744811300001)、、Scopus(收录号：2-s2.0-85123097706)、WOS

基金：This study was supported by the Major R&D Project of Zhejiang Province (no. 2019C03040) and the Zhejiang Province Bureau of Health (no. 2020KY1030).

语种：英文

外文关键词：Giant gastric subepithelial tumors; Endoscopic resection; Endoscopic full-thickness resection; Endoscopic submucosal dissection

外文摘要：Background and aims Currently, published data of endoscopic resection (ER) for giant (>= 6 cm) gastric subepithelial tumors originating from the muscularis propria layer (MP-SETs) are extremely rare and limited to only case reports. The aim of this study was thus to assess the feasibility of using ER for giant (>= 6 cm) gastric MP-SETs in a case series. Methods Between July 2013 and December 2020, a total of 23 patients with giant (>= 6 cm) gastric MP-SETs were treated with ER in the endoscopic center of Taizhou hospital. The study assessed outcomes of en bloc resection, complete resection, total complications, and local residual/recurrence of tumors. Results The mean procedure time was 112.2 min. En bloc resection was achieved in 22 tumors (95.7%). En bloc removal from the stomach and complete resection were achieved in 6 patients (26.1%). The rate of complete resection differed significantly depending on the minimum tumor diameter (P < 0.001). During hospitalization, 4 patients had complications, including localized peritonitis (3/23, 13.0%) and pulmonary infection (1/23, 4.3%). These 4 patients recovered successfully after conservative medical treatment. Histopathological examination revealed that 18 tumors were gastrointestinal stromal tumors (GISTs), and 5 tumors were leiomyoma. No patients were observed to have residual or recurrent tumors during the follow-up. Conclusions Although ER for giant (>= 6 cm) gastric MP-SETs was associated with several technical challenges and a relatively low complete resection rate, this technique was found to be a feasible therapeutic method for selected patients with a giant (>= 6 cm) gastric MP-SETs when performed by an experienced endoscopic team.