文献类型：期刊文献

中文题名：羊栖菜提取物的降血糖作用研究

英文题名：Study on the Hypoglycemic Effect of the Extract of Sargassum fusiforme

作者：张华芳[1]

机构：[1]绍兴文理学院

年份：2006

卷号：17

期号：2

起止页码：F0003

中文期刊名：时珍国医国药

外文期刊名：LiShiZhen Medicine and Materia Medica Research

收录：北大核心2004、CSCD_E2011_2012、北大核心、CSCD

语种：中文

中文关键词：羊栖菜;提取物;四氧嘧啶;血糖

外文关键词：Sargassum fusiforme;Extract;Alloxan;Blood glucose

中文摘要：目的研究羊栖菜提取物对正常及四氧嘧啶所致糖尿病小鼠血糖的影响。方法用四氧嘧啶糖尿病小鼠为模型,以血糖、糖耐量为指标研究羊栖菜提取物的降血糖作用。结果羊栖菜提取物对正常小鼠无降血糖作用;预防性给予羊栖菜粗多糖(350,700 mg.kg-1)后,四氧嘧啶糖尿病小鼠血糖显著降低;羊栖菜粗多糖和醇提物(700 mg.kg-1)有治疗作用,能明显降低糖尿病小鼠血糖水平;对正常小鼠和糖尿病小鼠糖耐量无明显改善。结论羊栖菜提取物对四氧嘧啶糖尿病小鼠具有防治作用。

外文摘要：Objective to explore the effect of the extntct of Sargassum fusiforme（ESF）on blood glucose in diabetes mice.Methods Effect of ESF on alloxan-inducing diahetes mellitus model was investigated by blod glucose concentmtion and glucose tolerance test.Results ESF can＇t decrease the blood sugar level in normal mice.At doses of 350 and 700mg/kg,SFP（Sargassum fusiforme polysacharide） has prophylactic effect in diabetic mice.At dose of 700mg/kg,ESF reduces the blood glucose level significantly.Besides,there＇re no marked changes of the glucose tolerance in moral or diabetes mellitus mice Conclusion The results show that ESF are active components in protecting against alloxan-indueed pancreas injury and mediating the blood glucose level.