文献类型：期刊文献

英文题名：Cobalt-catalyzed O-arylation of N-protected amino alcohols with arenes via cross-dehydrogenative C-O coupling strategy: Direct access to aryloxyamines

作者：Wang, Chaoyu[1];Bei, Wenfeng[1];Li, Wanting[1];Wang, Dongwei[1];Liu, Yuqin[1];Gong, Zile[1];Zeng, Kailin[1];Feng, Ruokun[1];Huang, Xianqiang[2];Qi, Chenze[1,3]

机构：[1]Shaoxing Univ, Coll Chem & Chem Engn, Res Ctr Adv Catalyt Mat & Funct Mol Synth, Zhejiang Key Lab Alternat Technol Fine Chem Proc, Shaoxing 312000, Peoples R China;[2]Liaocheng Univ, Sch Chem & Chem Engn, Shandong Prov Key Lab Chem Energy Storage & Novel, Liaocheng 252059, Peoples R China;[3]Jiamusi Univ, Sch Pharm, Jiamusi 154007, Heilongjiang, Peoples R China

年份：2022

卷号：106

外文期刊名：TETRAHEDRON LETTERS

收录：SCI-EXPANDED(收录号：WOS:000861223800019)、、WOS、CCR-EXPANDED(收录号：WOS:000861223800019)

基金：This research was supported by Zhejiang Provincial Natural Science Foundation of China under Grant No. LQ15B020002, LGG18E030004 and Natural Science Foundation of China under Grant 21871125 and 61504082.

语种：英文

外文关键词：Cobalt -catalyzed; Amino alcohols; C -H arylation; Bidentate-chelation; Aryloxyamines

外文摘要：An efficient Co(II)-catalyzed cross-dehydrogenative C-O coupling strategy for the arylation of N-protected amino alcohols, including 1,2-, 1,3-and 1,4-amino alcohols, branched amino alcohols and cyclic amino alcohols with different amides derivatives has been developed, affording a wide range of corresponding aryloxyamines compounds with excellent convertibility in moderate to good yields, which are of great interest in medicinal and pharmaceutical chemistry. Furthermore, this reaction system could be further applied to the preparation of potential bioactive molecules. CO 2022 Elsevier Ltd. All rights reserved.