文献类型：期刊文献

英文题名：Body Mass Index mediates the associations between dietary approaches to stop hypertension and obstructive sleep apnea among US adults

作者：Li, Songtao[1];Yang, Yuxin[2];Lin, Mengying[3];Lv, Tian[4];Pan, Yourang[3];Zhou, Jie[4]

机构：[1]Med Coll Shaoxing Univ, Shaoxing Peoples Hosp 7, Affiliated Mental Hlth Ctr, Dept Psychiat, Shaoxing, Peoples R China;[2]Shaoxing Univ, Coll Med, Shaoxing, Peoples R China;[3]Shaoxing Univ, Shaoxing Peoples Hosp 7, Affiliated Mental Hlth Ctr,Med Coll, Dept Psychosomat, Shaoxing, Peoples R China;[4]Wenzhou Med Univ, Zhuji Affiliated Hosp, Dept Neurol, Zhuji, Peoples R China

年份：2024

卷号：11

外文期刊名：FRONTIERS IN NUTRITION

收录：SCI-EXPANDED(收录号：WOS:001385892100001)、、Scopus(收录号：2-s2.0-85213681619)、WOS

基金：The author(s) declare that financial support was received for the research, authorship, and/or publication of this article. This study was supported by the Zhejiang Provincial Medical and Health Science and Technology Project Fund (Grant No. 2023RC292).

语种：英文

外文关键词：OSA (obstructive sleep apnea); DASH (dietary approaches to stop hypertension); NHANES (National Health and Nutrition Examination Survey); BMI;Body Mass Index; mediation

外文摘要：Background: The Dietary Approaches to Stop Hypertension (DASH) are associated with reduced cardiovascular, diabetes risk, but the effect on obstructive sleep apnea (OSA) is uncertain. Methods: This study used data from the National Health and Nutrition Examination Survey (NHANES). DASH score was assessed through 24-h dietary recall interviews, and OSA diagnosis in individuals was based on predefined criteria. Logistic regression analysis was used to assess the association between DASH and OSA. Restricted cubic spline (RCS) analysis was used to investigate the dose-response relationship between DASH score and OSA risk. And comprehensive subgroup and mediation analyses were performed. Results: Among the 14,978 participants, 27.01% had OSA. DASH scores had a negative association with the risk of OSA (OR = 0.91, 95%CI: 0.88-0.95, p < 0.01). Next, we divided DASH scores into quintiles groups. In comparison to the reference group Q1, groups Q5 had adjusted OR values of 0.63 (95%CI: 0.52-0.76, p < 0.01). Subgroup analyses revealed that this association was consistent across different groups. Further mediation analyses showed that the associations of DASH with OSA risk parallelly mediated by the above Body Mass Index (BMI) 33.4%,95%CI (20.6-46.2%) (all p < 0.05). The restricted cubic spline (RCS) analysis indicated a significant dose-response relationship between DASH diet and OSA risk. Conclusion: These findings suggested that DASH decreased OSA risk, which was possibly and partly mediated by BMI.