文献类型：期刊文献

英文题名：An Efficient Synthesis of Spiro[indoline-3,9 '-xanthene]trione Derivatives Catalyzed by Magnesium Perchlorate

作者：Chen, Chunfeng[1,2];Lv, Chunlei[2];Liang, Jianfeng[2];Jin, Jianqing[2];Wang, Lijun[1];Wu, Chunlei[1];Shen, Runpu[1]

机构：[1]Shaoxing Univ, Dept Chem & Chem Engn, Shaoxing 312000, Zhejiang, Peoples R China;[2]Zhejiang Med Co Ltd, Shaoxing 312000, Zhejiang, Peoples R China

年份：2017

卷号：22

期号：8

外文期刊名：MOLECULES

收录：SCI-EXPANDED(收录号：WOS:000408602900060)、、Scopus(收录号：2-s2.0-85028056573)、WOS

基金：We gratefully acknowledge the financial support from Public Projects of Zhejiang Province of China (No. 2016C31032, NO. 2015C31147) and the National Natural Science Foundation of China (No. 51402195).

语种：英文

外文关键词：aqueous; isatin; spiro[indoline-3,9 '-xanthene]trione; magnesium perchlorate

外文摘要：A simple and efficient method for the synthesis of spiro[indoline-3,9'-xanthene]trione derivatives by means of condensation between isatins and 1,3-cyclohexanedione in the presence of a catalytic amount of magnesium perchlorate at 80 degrees C in 50% aqueous ethanol medium has been described. Notably, the present method offers desirable advantages of good yields, simplicity of workup procedure, easy purification, and reduced reaction times.