文献类型：期刊文献

中文题名：呋虫胺关键中间体的合成研究进展

英文题名：Progress in Synthesis of Significant Intermediates about Dinotefuran

作者：徐庆[1];冯高峰[1];金城安[1]

机构：[1]绍兴文理学院化学化工学院

年份：2018

卷号：40

期号：2

起止页码：132

中文期刊名：化学试剂

外文期刊名：Chemical Reagents

语种：中文

中文关键词：呋虫胺;3-羟甲基四氢呋喃;3-氨甲基四氢呋喃;合成方法

外文关键词：dinotefuran ; 3-hydroxymethyltetrahydrofuran ; 3-aminomethyltetrahydrofuran ; synthetic methods

中文摘要：呋虫胺是第三代新型烟碱类杀虫剂,具有高效、低毒、杀虫广谱等优点,广泛应用于各种农作物的病害虫防治。目前,国内外合成呋虫胺主要有3-羟甲基四氢呋喃衍生化法和3-氨甲基四氢呋喃衍生化法。然而,传统生产工艺存在绿色性差、收率低、三废多等缺点,严重限制了企业清洁化生产。改善反应的方向主要集中在关键中间体3-羟甲基四氢呋喃和3-氨甲基四氢呋喃的高效绿色合成。综述了近几年来呋虫胺关键中间体3-羟甲基四氢呋喃和3-氨甲基四氢呋喃的研究进展,比较了各自路线的优缺点,并对其合成方法进行了展望。

外文摘要：As the third-generation neonicotinoid insecticide,dinotefuran with many advantages,such as high-efficiency,low-toxicity,great insecticide and so on,which is widely used in pest control.Nowadays,there are two main methods for the synthesis of dinotefuran：3-hydroxymethyltetrahydrofuran and 3-aminomethyltetrahydrofuran derivatization reaction.However,there are lots of inferiorities in conventional manufacturing technology,such as unfriendly environment,low yield,tremendous pollution,which are bad for cleaning production.Therefore,the green and efficient preparation methods for significant chemical intermediates of dinotefuran are focused.This work talks about the synthetic methods about significant chemical intermediates of dinotefuran：3-hydroxymethyltetrahydrofuran and 3-aminomethyltetrahydrofuran.Comparation of the merits and shortcomings,and the prospect for synthesis methods are discussed.