文献类型：期刊文献

英文题名：Phylogenetic analyses of the 19 STR loci in X chromosome revealed discriminant forensic characteristics for Chinese Daur and Oroqen minorities

作者：Liu, Yang[1,2];Ye, Yi[3];Yi, Xiao-Qin[3];Zhang, Jia-Hui[4];Fan, Guang-Yao[2];Hao, Dong-Yun[1]

机构：[1]Harbin Normal Univ, Coll Life Sci & Technol, Key Lab Mol Cytogenet & Genet Breeding Heilongjia, Harbin 150025, Heilongjiang, Peoples R China;[2]Shaoxing Univ, Coll Med, Forens Ctr, 508 Huancheng West Rd, Shaoxing 312000, Zhejiang, Peoples R China;[3]Sichuan Univ, Dept Forens Toxicol Anal, West China Sch Basic Med Sci & Forens Med, Chengdu 610041, Sichuan, Peoples R China;[4]Shaoxing Univ, Coll Med, 508 Huancheng West Rd, Shaoxing 312000, Zhejiang, Peoples R China

年份：2022

卷号：136

期号：2

起止页码：551

外文期刊名：INTERNATIONAL JOURNAL OF LEGAL MEDICINE

收录：SCI-EXPANDED(收录号：WOS:000695121500002)、、Scopus(收录号：2-s2.0-85114922324)、WOS

基金：This study was funded by opening project of the Shanghai Key Laboratory of Forensic Medicine [grant number KF1909] and the 2017 Research Program of Shaoxing University (2017LG1009).

语种：英文

外文关键词：Forensic efficiency; Phylogenetic analyses; X-chromosomal STR; Daur people; Oroqen people

外文摘要：In respect of forensic genetics, X-STRs are widely applied for deficiency paternity cases. Given the popularization of AGCU-X19 STR Kit in China, there has been investigation conducted into the genetic data and forensic parameters of 19 X-STR loci in many of the Chinese ethnic groups, which makes it possible to perform nationwide phylogenetic comparation. To evaluate the allele and haplotype diversity of 19 X-STR loci and to explore their forensic efficiency in the Daur and Oroqen minorities, unrelated healthy Daur (n = 86) and Oroqen (n = 165) individuals were recruited from Heilongjiang province, so as to reveal the phylogenetic relationship between the two minorities and other Chinese ethnic groups. Of the Daur and Oroqen minorities, 172 and 183 alleles at the 19 X-STR loci were observed, respectively. Haplotype diversity exceeded 0.9 among all the linkage clusters. High cumulative value was observed for the power of discrimination, the probability of exclusion, and the mean exclusion chance for deficiency cases (normal trios and duo cases). As revealed by this study, the panel of 19 X-STR loci is an effective supplementary tool for the kinship test of the studied nationalities.