文献类型：期刊文献

英文题名：Pd(II)-Catalyzed Denitrogenative and Desulfinative Addition of Arylsulfonyl Hydrazides with Nitriles

作者：Meng, Mengting[1];Yang, Liangfeng[1];Cheng, Kai[1];Qi, Chenze[1]

机构：[1]Shaoxing Univ, Zhejiang Key Lab Alternat Technol Fine Chem Proc, Shaoxing 312000, Peoples R China

年份：2018

卷号：83

期号：6

起止页码：3275

外文期刊名：JOURNAL OF ORGANIC CHEMISTRY

收录：SCI-EXPANDED(收录号：WOS:000428002800028)、、EI(收录号：20181204928455)、Scopus(收录号：2-s2.0-85044137556)、WOS、CCR-EXPANDED(收录号：WOS:000428002800028)

基金：This work was supported by the National Natural Science Foundation of China (no. 21402123), the Zhejiang Provincial Natural Science Foundation of China (nos. LY18B020006 and LQ14B020001), and the Science Technology Project of Shaoxing City (no. 2017B70053).

语种：英文

外文关键词：Addition reactions - Catalysis - Cyanides - Ketones

外文摘要：A Pd(II)-catalyzed denitrogenative and desulfinative addition of arylsulfonyl hydrazides with nitriles has been successfully achieved under mild conditions. This transformation is a new method for the addition reaction to nitriles with arylsulfonyl hydrazides as arylating agent, thus providing an alternative synthesis of aryl ketones. The reported addition reaction is tolerant to many common functional groups, and works well in the presence of electron-donating and electron withdrawing substituents. Notably, the reported denitrogenative and desulfinative addition was also appropriate for alkyl nitriles, making this newly developed transformation attractive.