文献类型：期刊文献

中文题名：老年心力衰竭感染患者血钠、B型钠尿肽、尿酸的水平与心功能的相关性研究

英文题名：Correlation analysis between serum sodium,plasma BNP,serum uric acid and cardiac function of the senile heart failure patients with infections

作者：周云[1];付永平[1];沙振球[1]

机构：[1]绍兴文理学院附属医院心内科

年份：2015

卷号：25

期号：8

起止页码：1798

中文期刊名：中华医院感染学杂志

外文期刊名：Chinese Journal of Nosocomiology

收录：CSTPCD、、北大核心2014、北大核心、CSCD_E2015_2016、CSCD

基金：浙江省卫生厅基金资助项目(2013KYB269)

语种：中文

中文关键词：心力衰竭;感染;血钠;B型钠尿肽

外文关键词：Heart failure; Infection; Blood NA; B type natriuretic peptide

中文摘要：目的探讨血钠(Na)、B型钠尿肽(BNP)、尿酸(UA)在老年心力衰竭感染中的表达及与心功能的关系,以降低老年心力衰竭的感染率。方法选取2010年1月-2014年1月50例老年心力衰竭感染患者为感染组,同期选择50例老年心力衰竭无感染患者为疾病非感染组,选择50名健康人群为对照组;检测受试者血Na、BNP、UA水平,采用SPSS 17.0软件进行分析。结果感染组患者血BNP、UA水平高于非感染组和对照组,差异有统计学意义(P<0.01);非感染组患者血Na水平明显低于对照组,差异有统计学意义(P<0.01);感染组患者血BNP、UA水平高于非感染组,差异有统计学意义(P<0.01);感染组患者血NA水平明显低于非感染组,差异有统计学意义(P<0.01)。结论血BNP、UA在老年心力衰竭感染中呈高表达,而血Na在老年心力衰竭感染中呈下降趋势,血Na、BNP、UA与老年心力衰竭感染病情及进展密切相关。

外文摘要：OBJECTIVE To study the change of the level of serum sodium,plasma BNP,serum uric acid in elderly heart failure patients after being infected and the correlation between them and heart functions so as to decrease the infection rate in elderly heart failure.METHODS From Jan.2011 to Jan.2014,totally 50 cases of elderly patients with heart failure and being infected were selected as infection group,and another 50 cases of senile heart failure patients who were not infected were selected as non-infection group in the same period,and 50 cases of healthy people were selected as control group.Serum sodium,plasma BNP,serum uric acid were tested,and all data were analyzed by SPSS 17.0software.RESULTS The bloods BNP,UA levels in the infection group were higher than that of the non-infection group and control group.The differences were significant（P〈0.01）.And the blood NA level in the non-infection group was significantly lower than the control group（P〈0.01）.The blood BNP and UA levels in the infection group were significenfly higher than that of the non-infection group（P〈0.01）.And the blood NA level in the infection group was lower than the non-infection group.The difference was statistically significant（P〈0.01）.CONCLUSIONBlood BNP and UA are highly expressed in elderly patients with heart failure combined with infections,while Na decreased in the process of infections.Na,BNP and uric acid are closely related to the senile congestive heart failure with infections and the severity of illness.