文献类型：期刊文献

英文题名：Carbamoyl Radicals via Photoredox Decarboxylation of Oxamic Acids in Aqueous Media: Access to 3,4-Dihydroquinolin-2(1H)-ones

作者：Bai, Qa-Fan[1];Jin, Chengan[1];He, Jing-Yao[1];Feng, Gaofeng[1]

机构：[1]Shaoxing Univ, Zhejiang Key Lab Alternat Technol Fine Chem Proc, Shaoxing 312000, Peoples R China

年份：2018

卷号：20

期号：8

起止页码：2172

外文期刊名：ORGANIC LETTERS

收录：SCI-EXPANDED(收录号：WOS:000430898200011)、、WOS、CCR-EXPANDED(收录号：WOS:000430898200011)

基金：Financial support by Shaoxing University for supporting the National Natural Science Foundation of China (No. 21302130) is acknowledged with thanks. We thank Prof. Jian Jin (Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences) for discussions and help.

语种：英文

外文摘要：The first visible-light-mediated photoredox oxidative approach for generating carbamoyl radicals from oxamic acids is disclosed. Reaction of the generated carbamoyl radicals with electron-deficient alkenes opens efficient access to 3,4-dihydroquinolin-2(1H)-ones under mild conditions through a sequence of intermolecular radical addition,cyclization, and aromatization. The process is compatible with a variety of oxamic acids and electron-deficient alkenes, and a wide variety of 3,4-dihydroquinolin-2(1H)-ones were prepared.