文献类型：期刊文献

英文题名：CuCl2 center dot 2H(2)O/TBHP mediated synthesis of beta-enaminones via coupling reaction of vinyl azides with aldehydes

作者：Zhang, Yaohong[1];Luo, Mengqiang[1,2];Zhang, Yichan[3];Cheng, Kai[1];Li, Yong[1];Qi, Chenze[1];Shen, Runpu[2];Wang, Hai[1]

机构：[1]Shaoxing Univ, Sch Chem & Chem Engn, Sch Life Sci, Zhejiang Key Lab Alternat Technol Fine Chem Proc, Shaoxing 312000, Zhejiang, Peoples R China;[2]Shaoxing Univ, Zhejiang Engn Res Ctr Fat Soluble Vitamin, Sch Chem & Chem Engn, Shaoxing 312000, Zhejiang, Peoples R China;[3]Yancheng Inst Technol, Dept Chem & Chem Engn, Yancheng 224051, Jiangsu, Peoples R China

年份：2022

卷号：20

期号：9

起止页码：1952

外文期刊名：ORGANIC & BIOMOLECULAR CHEMISTRY

收录：SCI-EXPANDED(收录号：WOS:000755738500001)、、WOS、CCR-EXPANDED(收录号：WOS:000755738500001)

基金：The work was financially supported by the Natural Science foundation of Zhejiang Province (No. LQ16H090004) and the National Natural Science Foundation of China (No. 12075154 and No. 21801167).

语种：英文

外文摘要：A facile and efficient oxidative functionalization of vinyl azides with aldehydes furnishing a diverse array of beta-acylated enaminones was developed. The cross coupling was accomplished in the presence of CuCl2 center dot 2H(2)O/TBHP and produced the desired beta-acylated enaminones in a (Z)-stereo-selective and atom-economic manner, which make this protocol particularly attractive. In the transformation, the new C-C and C-N bonds were formed via a one-pot strategy including the process of radical addition and recombination.