文献类型：期刊文献

英文题名：Climate warming fuels the global antibiotic resistome by altering soil bacterial traits

作者：Lin, Da[1,2];Du, Shuai[1,3];Zhao, Zhe[4];Zhang, Tianlun[1,2];Wang, Lu[1,3];Zhang, Qi[5];Zhou, Shu-Yi-Dan[6];Graham, David W.[7];Tissue, David T.[8];Zhu, Dong[1,3];Zhu, Yong-Guan[1,3,4];Penuelas, Josep[9,10];Reich, Peter B.[11,12,13,14]

机构：[1]Chinese Acad Sci, Inst Urban Environm, State Key Lab Reg & Urban Ecol, Ningbo Observat & Res Stn, Xiamen, Peoples R China;[2]Univ Chinese Acad Sci, Beijing, Peoples R China;[3]CAS Haixi Ind Technol Innovat Ctr Beilun, Zhejiang Key Lab Urban Environm Proc & Pollut Cont, Ningbo, Peoples R China;[4]Chinese Acad Sci, Res Ctr Ecoenvironm Sci, State Key Lab Urban & Reg Ecol, Beijing, Peoples R China;[5]Shaoxing Univ, Coll Chem & Chem Engn, Shaoxing, Peoples R China;[6]Chinese Acad Sci, Guangdong Prov Key Lab Appl Bot, South China Bot Garden, Guangzhou, Peoples R China;[7]Univ Durham, Dept Biosci, Durham, England;[8]Western Sydney Univ, Hawkesbury Inst Environm, Richmond, Australia;[9]CSIC, Global Ecol Unit CREAF CSIC UAB, Barcelona, Spain;[10]Univ Autonoma Barcelona, CREAF, Barcelona, Spain;[11]Univ Michigan, Inst Global Change Biol, Ann Arbor, MI USA;[12]Univ Michigan, Sch Environm & Sustainabil, Ann Arbor, MI USA;[13]Univ Minnesota, Dept Forest Resources, St Paul, MN USA;[14]Western Sydney Univ, Hawkesbury Inst Environm, Sydney, NSW, Australia

年份：2025

外文期刊名：NATURE ECOLOGY & EVOLUTION

收录：SCI-EXPANDED(收录号：WOS:001502013700001)、、Scopus(收录号：2-s2.0-105007248442)、WOS

基金：We acknowledge the funds of the National Natural Science Foundation of China (grant nos. 42222701 to D.Z. and 42090063 to Y.-G.Z.), J.P. was supported by the Catalan Government grant no. SGR2021-1333, Youth Innovation Promotion Association, Chinese Academy of Sciences (grant no. 2023321 to D.Z.), Ningbo Yongjiang Talent Project (grant no. 2022A-163-G to D.Z.) and Ningbo S&T project (grant no. 2021-DST-004 to Y.-G.Z.).

语种：英文

外文摘要：Understanding the implications of global warming on the spread of antibiotic resistance genes (ARGs) and virulence factor genes (VFGs) within soil ecosystems is crucial for safeguarding human well-being and sustaining ecosystem health. However, there is currently a lack of large-scale, systematic underpinning data needed to examine this issue. Here, using an integrative approach that combines field experiments, extensive global metagenomic data and microbial culturing, we show that warming enriches bacteria with ARGs and VFGs, increases metabolic complexity and adaptability in bacteria, and accelerates genetic alterations related to ARG and VFGs development. Our validation experiments confirm that the warming effect is more pronounced in colder regions. Machine learning predictions further suggest that warming will increase the soil ARG abundance, especially in some areas that rely heavily on fossil fuels. These results suggest another major negative consequence of global warming, highlighting the importance of developing and implementing sustainability policies that simultaneously combat climate change and antibiotic resistance.