文献类型：期刊文献

英文题名：Underestimated incidence of kidney disease in nonrenal outpatient

作者：Lu, Zeyuan[1];Yin, Jianyong[1];Zhang, Guangyuan[2];Wu, Rui[1];Zhao, Qing[3];Wang, Niansong[1];Yan, Chungen[4];Wang, Feng[1,5]

机构：[1]Shanghai Jiao Tong Univ, Affiliated Peoples Hosp 6, Dept Nephrol, Shanghai, Peoples R China;[2]Southeast Univ, Zhongda Hosp, Dept Urol, Nanjing, Jiangsu, Peoples R China;[3]Shanghai Jiao Tong Univ, Affiliated Peoples Hosp 6, Dept Cardiol, Shanghai, Peoples R China;[4]Shaoxing Univ, Dept Internal Med, Sch Med, Shaoxing, Peoples R China;[5]Shanghai Eighth Peoples Hosp, Dept Nephrol, Shanghai, Peoples R China

年份：2017

卷号：39

期号：1

起止页码：328

外文期刊名：RENAL FAILURE

收录：SCI-EXPANDED(收录号：WOS:000394441100046)、、Scopus(收录号：2-s2.0-85016444973)、WOS

基金：This work was supported by the National Natural Science Foundation of China [81570603 and 81670632], the New-100 talent Plan of Shanghai Jiao Tong University School of Medicine, Shanghai talents development fund and Shanghai Pujiang Talent Projects [15PJ1406700], Health and Family Planning Commission of Jiangsu Province Foundation [Z201609].

语种：英文

外文关键词：Kidney injury; chronic kidney disease; hypertension; diabetes mellitus; coronary disease

外文摘要：Background and aims: Chronic kidney disease (CKD) has been regarded as a severe threaten to public health, a large percentage of CKD are secondary to other diseases. Serum creatinine is the most common marker of renal function, but it did not always reflect glomerular filtration rate (GFR) accurately. In order to investigate the prevalence of kidney disease in non-renal departments and to provide a basis for the prevention of kidney injury, the present study was conducted in several medical centers. Methods: A total of 17,462 outpatients were selected randomly from the departments of cardiology, endocrinology, and neurology in 16 hospitals and the incidence of kidney disease was screened. Estimated GFR (eGFR) was calculated by using MDRD-formula. Results: There are 5293 (30.1%) patients' eGFR above 90mL/min/1.73m(2) among all the subjects in non- renal departments, and 4055(23%) patients' eGFR lower than 60 mL/min/1.73m(2) including 80 patients whose eGFR were below 15 mL/min/1.73m(2). Furthermore, among 16616 subjects who have a normal SCr level, there are 3209 respondents' eGFR lower than 60 mL/min/1.73m(2). Moreover, individuals with hypertension or diabetes had a high prevalence of decreased renal function. Conclusions: This survey indicated kidney injury wildly existed in non- renal outpatients, and the incidence of CKD is underestimated.