文献类型：期刊文献

英文题名：An overview of the material science and knowledge of nanomedicine, bioscaffolds, and tissue engineering for tendon restoration

作者：Liang, Wenqing[1];Zhou, Chao[2];Meng, Yanfeng[3];Fu, Lifeng[4];Zeng, Bin[1];Liu, Zunyong[1];Ming, Wenyi[1];Long, Hengguo[1]

机构：[1]Zhejiang Chinese Med Univ, Zhoushan Hosp Tradit Chinese Med, Dept Orthoped, Zhoushan, Zhejiang, Peoples R China;[2]Zhoushan Guanghua Hosp, Dept Orthoped, Zhoushan, Zhejiang, Peoples R China;[3]Shaoxing Univ, Affiliated Hosp, Dept Orthoped, Shaoxing, Zhejiang, Peoples R China;[4]Shaoxing City Keqiao Dist Hosp Tradit Chinese Med, Dept Orthoped, Shaoxing, Zhejiang, Peoples R China

年份：2023

卷号：11

外文期刊名：FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY

收录：SCI-EXPANDED(收录号：WOS:001021124900001)、、EI(收录号：20232714365213)、Scopus(收录号：2-s2.0-85163924233)、WOS

基金：This work was supported by Public Technology Applied Research Projects of Zhejiang Province (LGF22H060023 to WL), Medical and Health Research Project of Zhejiang Province (2022KY433 to WL, 2021KY1164 to LF, 2023KY1303 to HL), Traditional Chinese Medicine Science and Technology Projects of Zhejiang Province (2022ZB382 to WL, 2023016295 to WM), Research Fund Projects of The Affiliated Hospital of Zhejiang Chinese Medicine University (2021FSYYZY45 to WL), Science and Technology Project of Zhoushan (2022C31034 to CZ, 2021C31099 to BZ).

语种：英文

外文关键词：tendon injuries; bioscaffolds; nanomedicine; biomaterials; tendon reengineering

外文摘要：Tendon wounds are a worldwide health issue affecting millions of people annually. Due to the characteristics of tendons, their natural restoration is a complicated and lengthy process. With the advancement of bioengineering, biomaterials, and cell biology, a new science, tissue engineering, has developed. In this field, numerous ways have been offered. As increasingly intricate and natural structures resembling tendons are produced, the results are encouraging. This study highlights the nature of the tendon and the standard cures that have thus far been utilized. Then, a comparison is made between the many tendon tissue engineering methodologies proposed to date, concentrating on the ingredients required to gain the structures that enable appropriate tendon renewal: cells, growth factors, scaffolds, and scaffold formation methods. The analysis of all these factors enables a global understanding of the impact of each component employed in tendon restoration, thereby shedding light on potential future approaches involving the creation of novel combinations of materials, cells, designs, and bioactive molecules for the restoration of a functional tendon.