文献类型：期刊文献

英文题名：Synthesis of Norcantharidin-dimer Derivatives

作者：Deng, Liping[1,2];Yong, Zhang[1];Tao, Weifeng[2];Shen, Jianfeng[3];Wang, Wei[2]

机构：[1]Shaoxing Univ, Chem & Chem Engn Inst, Dept Pharmacol, Shaoxing 312000, Zhejiang, Peoples R China;[2]Zhejiang Supor Pharmaceut, Shaoxing 312000, Zhejiang, Peoples R China;[3]Zhejiang Zhenyuan Pharmaceut, Shaoxing 312000, Zhejiang, Peoples R China

年份：2011

卷号：48

期号：1

起止页码：158

外文期刊名：JOURNAL OF HETEROCYCLIC CHEMISTRY

收录：SCI-EXPANDED(收录号：WOS:000287169400022)、、Scopus(收录号：2-s2.0-79251575012)、WOS、CCR-EXPANDED(收录号：WOS:000287169400022)

语种：英文

外文摘要：We use one molecule of ethylene diamine as a connecting arm to combine two molecules of 5,6-dehydronorcantharidin. Then, ten novel norcantharidin derivatives were synthesized in a single step by the [3 + 2] 1,3-dipolar cycloaddition reaction with oxime or hydrazone in the presence of chloramine-T, which is simpler than the conventional method.