文献类型：期刊文献

中文题名：海藻酸盐基非织造医用敷料的研究进展

英文题名：Research progress in alginate-based nonwoven medical dressings

作者：王惠婷[1];陈宇鉴[1];刘诗仪[2];张显涛[3];陆斌[4];邹专勇[1];王建[1];张寅江[1,5]

机构：[1]绍兴文理学院浙江省清洁染整技术研究重点实验室,浙江绍兴312000;[2]绍兴福清卫生用品有限公司,浙江绍兴312000;[3]振德医疗用品股份有限公司,浙江绍兴312000;[4]杭州杭纺科技有限公司,浙江杭州310000;[5]武汉纺织大学生物质纤维与生态染整湖北省重点实验室,湖北武汉430200

年份：2025

卷号：46

期号：6

起止页码：240

中文期刊名：纺织学报

外文期刊名：Journal of Textile Research

收录：北大核心2023、、北大核心

基金：浙江省科技厅领雁研发攻关计划项目(2022C01SA691301);湖北省重点实验室开发基金项目(STRZ202207);绍兴市产业关键技术攻关专项项目(2024B13006);绍兴文理学院-浙江大学绍兴研究院联合科研资助基金项目(2023LHLG008);绍兴文理学院研究生科研课题(Y20220702,Y20240256)。

语种：中文

中文关键词：医用纺织品;海藻酸盐;非织造医用敷料;抑菌;结构设计;特殊功能

外文关键词：medical textile;alginate;nonwoven medical dressing;bacteriostasis;structural design;special function

中文摘要：为推动海藻酸盐基非织造医用敷料的应用与发展,首先从结构出发,阐述海藻酸盐拥有较多羧羟基,适合离子交换与功能改性。其次综合分析海藻酸盐基非织造敷料种类,包括纯海藻酸纤维类、与其它纤维共混类、后整理改性类及纳米纤维类等。同时介绍了目前海藻酸盐基非织造敷料制备方法,包括纺丝法、梳理加固法、后整理法与复合法等。最后分析了通过添加抗菌剂或对海藻酸盐改性提升其抑菌性能,采用结构设计优化伤口愈合环境与使用便捷性,添加成分使敷料拥有特殊功能及实现智能化。

外文摘要：Significance With the increasing of the aged population,common diseases such as bedsores and diabetic ulcers are seen more frequently,and market demand for new medical dressings effective in dealing with such problems is increasing.Traditional or single functional medical dressings are difficult to meet the needs of the public.Alginate is widely used for manufacturing medical dressings because of its good biocompatibility,hemostatic and bacteriostatic properties.Nonwoven materials can be processed in a wide range,and the material is soft,breathable and comfortable,suitable for use in medical dressing substrates.Therefore,alginate-based nonwoven medical dressings play an increasingly important role in the treatment of wound bedsores and body surface ulcers.Progress As a natural polymer polysaccharide,alginate has many carboxylic and hydroxyl groups and is suitable for ion exchange and functional modification.Meanwhile,it has good biocompatibility and degradability,which makes it show great potential in the application field of medical dressing.The nonwoven material has simple preparation process,soft,breathable and comfortable,and is suitable for medical dressing.At present,alginate-based nonwoven dressings can be roughly divided into pure alginate fiber dressings,alginate fiber and other fiber mixed dressings,alginate finishing modified dressings and alginate nanofiber nonwoven dressings.The preparation methods mainly include spinning(electrospinning,microfluidic spinning,centrifugal spinning),carding and strengthening(needling,spunlace),finishing and compound methods.The alginate-based nonwoven dressing has great hemostatic ability,but has insufficient antibacterial ability,which can be modified by alginate derivative or add antibacterial agents to solve the problem in the future.Secondly,the use of diverse nonwoven substrate structures for medical dressings can effectively improve wound healing.Thirdly,materials with specific functions are added to give alginate-based nonwoven medical dressings corresponding functions,expand the application range of medical dressings,and achieve intelligentization of the dressings.The development of multi-functional intelligent dressings(anti-seawater immersion,great water vapor transmission rate,improving immunity,monitoring wound pH value changes,reducing scars,moistening sores,promoting blood coagulation)is an important future development direction.As a new medical dressing,alginate-based nonwoven medical dressing has a favorable development prospect.Conclusion and Prospect At present,there are many types of alginate-based nonwoven medical dressings associated with various preparation methods.The new multi-functional and integrated alginate-based nonwoven medical dressings are the development direction of medical dressings.In the future,it should actively search for natural antibacterial agents or other new antibacterial agents with wide sources and great non-toxic bacteriostatic performance,or modify alginate to strengthen bacteriostatic performance.The structural design of the innovative alginate-based nonwoven medical dressing achieves the most suitable wound healing environment and maximizes patient convenience.At the same time,by adding specific functional components to medical dressings,the dressings have special functions and realize intelligence on the basis of basic functions,and meet the needs of special wounds.