文献类型：期刊文献

英文题名：Effects of the molecular structure of graft-quaternization double modified chitosan on the functional properties of electrospun antibacterial nanofiber

作者：Li, Manli[1,2,4,5];Zhu, Shengbin[1,2];Li, Xiaohong[3];Jin, Enqi[1,4,5]

机构：[1]Shaoxing Univ, Coll Text & Apparel, Shaoxing 312000, Peoples R China;[2]Key Lab Clean Dyeing & Finishing Technol Zhejiang, Shaoxing 312000, Peoples R China;[3]Shaoxing Yongfeng Text Printing & Dyeing Co Ltd, Shaoxing 312073, Peoples R China;[4]Shaoxing Univ, Natl Engn Res Ctr Fiber Based Composites, Shaoxing Subctr, Shaoxing, Zhejiang, Peoples R China;[5]Shaoxing Univ, Natl Carbon Fiber Engn Technol Res Ctr, Zhejiang Subctr, Shaoxing, Peoples R China

年份：2024

外文期刊名：IRANIAN POLYMER JOURNAL

收录：SCI-EXPANDED(收录号：WOS:001318536700001)、、EI(收录号：20243917096651)、Scopus(收录号：2-s2.0-85204598414)、WOS

基金：This work was financially supported by Technological Research Project for Public Welfare of Zhejiang Province (LGG21E030005; LGG22E030002), Scientific and Technological Research Project for Public Welfare of Shaoxing (2022A12004), "Spearhead and Leading Goose + X" Research and Development Project of Zhejiang Province (2024C02007), and Postdoctoral Research Program of Zhejiang Province of China (276089).

语种：英文

外文关键词：Chitosan; Amino-containing acrylate; Chloralkane; Graft polymerization; Quaternization; Antibacterial property

外文摘要：Graft polymerization-quaternization double modification has become a new effective method for preparing antibacterial chitosan (CS) in recent years. To improve the properties of double modified CS, the effects of molecular structures of amino-containing acrylate (ACA) monomer grafted onto CS (CS-g-PACA) and a quaternary ammonium reagent used for the quaternization of CS-g-PACA have been investigated in the study. A series of ACA monomers, i.e., dimethylaminoethyl methacrylate (DMAEMA), diethylaminoethyl methacrylate (DEAEMA) and 2-(tert-butyl amino)ethyl methacrylate (TBAEMA), were firstly grafted onto the molecular chain of CS. Then, CS-g-PACA was quaternized by various quaternary ammonium reagents, i.e., three kinds of chloralkane include 1-chlorobutane, 1-chlorooctane and 1-chlorododecane. The modified CS was blended with PVA to prepare nanofiber membranes by electrospinning. The major functional properties of the nanofiber membranes, e.g., fiber morphology, thermal stability, tensile property, water stability, and inhibition of E.coli and S.aureus as representatives of gram negative and positive bacterial, were evaluated systematically. The results showed that when ACA and chloralkane were TBAEMA and 1-chlorobutane, respectively, the graft-quaternization double modified CS/PVA blend nanofiber membrane possessed a more uniform and smooth fiber structure, higher thermal stability, tensile strength, water stability, and better inhibition function to the bacteria. For instance, the diameter of the fiber could reach similar to 180 nm and tensile strength of the fiber membrane could touch the value of 20.1 MPa as well. The inhibition rate of E.coli and S.aureus was as high as 95.9% and 99.6%, respectively. Double modified CS nanofibers have shown great potential to be used as biocompatible and environment-friendly medical and hygiene textiles. [GRAPHICS] .