文献类型：期刊文献

英文题名：Thiol-yne click reaction mediated photoelectrochemical detection of multi-sulfhydryl compounds based on diacetylene functionalized conjugated polymer

作者：Tang, Junyan[1];Yin, Shuyi[1];Liu, Xiaoya[1];Kan, Zigui[1];Zhang, Xicheng[1];Jiang, Mengnan[1];Tao, Feifei[3];Wang, Fei[1];Li, Caolong[1,2]

机构：[1]China Pharmaceut Univ, Sch Sci, Key Lab Biomed Funct Mat, Nanjing 211198, Peoples R China;[2]Tibetan Tradit Med Coll, Tibetan Med Res Inst, Tibet 850000, Peoples R China;[3]Shaoxing Univ, Dept Chem & Chem Engn, Shaoxing 312000, Peoples R China

年份：2021

卷号：344

外文期刊名：SENSORS AND ACTUATORS B-CHEMICAL

收录：SCI-EXPANDED(收录号：WOS:000679303300007)、、EI(收录号：20212310455144)、Scopus(收录号：2-s2.0-85107126888)、WOS

基金：We appreciate the financial support by the National Key Research and Development Project (2019YFC0312602) and National Natural Science Foundation of China (51372154) . The work is also supported by National Innovation and Enterpreneurship Training Program for Un-dergraduate (202110316006Z) .

语种：英文

外文关键词：1,3-diyne; Conjugated microporous polymers; pi-pi interaction; Photoelectrochemistry; Thiol-yne; Click reaction

外文摘要：Most existing solutions for thiol detection require the addition of extra chemical agents to produce detection signals. However, the tedious operations in the sensing process are unfavorable for the real-time dynamic detection of thiol molecules. Herein, we present an all-organic graphene/poly(1,3,5-triethynylbenzene) (PTEB) composite for rapid and direct photoelectrochemical (PEC) analysis of multi-sulfhydryl compounds through specific thiol-yne click reaction. The non-covalent interfacial pi-pi interaction between the graphene and PTEB improves the optoelectronic properties of PTEB, which sensitizes the photocathode toward thiol detection with high sensitivity, broad linear range, and low detection limit. The theoretical calculation reveals that abundant 1,3-diyne linkages of PTEB are -SH sensitive active sites in PEC detection. Furthermore, a homemade sensing instrument has achieved real-time monitoring of thiol, suggesting its feasibility as an online sensor or a reaction monitor embedded in the industrial production line. Such progress holds promise for developing a diacetylene functionalized conjugated polymers-based -SH responsive platform for practical application in chemical production and quality control.