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Clinical outcomes of endoscopic versus laparoscopic resection for senile patients with gastric gastrointestinal stromal tumours (2 to 4 cm) originating from the muscularis propria layer     被引量:3

文献类型:期刊文献

英文题名:Clinical outcomes of endoscopic versus laparoscopic resection for senile patients with gastric gastrointestinal stromal tumours (2 to 4 cm) originating from the muscularis propria layer

作者:Meng, Xi[1];Hu, Yun-Fei[1];Mao, Xin-Li[1,2];Zheng, Hai -Hong[3];Zhou, Shen-Kang[4];Zhang, Yu[1,2]

机构:[1]Shaoxing Univ, Sch Med, Shaoxing, Zhejiang, Peoples R China;[2]Taizhou Hosp Zhejiang Prov, Wenzhou Med Coll, Linhai, Zhejiang, Peoples R China;[3]Taizhou Hosp Zhejiang Prov, Wenzhou Med Coll, Dept Pathol, Linhai, Zhejiang, Peoples R China;[4]Taizhou Hosp Zhejiang Prov, Wenzhou Med Coll, Dept Gastrointestinal Surg, Linhai, Zhejiang, Peoples R China

年份:2022

卷号:17

期号:3

起止页码:196

外文期刊名:GASTROENTEROLOGY REVIEW-PRZEGLAD GASTROENTEROLOGICZNY

收录:ESCI(收录号:WOS:000864077300004)、Scopus(收录号:2-s2.0-85138631516)、WOS

基金:Acknowledgments This study was supported by the Major R&D Project of Zhejiang Province (no. 2019C03040) and the Zheji- ang Province Bureau of Health (no. 2020KY1030) .

语种:英文

外文关键词:GISTs; endoscopic resection; laparoscopic resection

外文摘要:Introduction: Currently, there still are no selection criteria for endoscopic resection (ER) versus laparoscopic resection (LR) of gastric gastrointestinal stromal tumours (GIST) (2 to 4 cm) originating from the muscularis propria layer (MP-GISTs). Aim: To investigate and compare the long-term prognosis of ER and LR for resecting gastric MP-GISTs, with at least 5 years of follow-up. Material and methods: Between January 2010 and December 2015, 134 patients with gastric MP-GISTs were consecutively enrolled in this study. The main comparison measurements included the short-term and long-term outcomes between the ER group (n = 89) and the LR group (n = 45). Results: In this study, there were no significant differences in the rates of complete resection (p = 0.220) and short-term complications (p = 0.663) between the ER group and the LR group. The ER group had a shorter operation time (50.1 +/- 18.2 min vs. 120.6 +/- 32.5 min, p < 0.001), shorter hospital stays (5.1 +/- 1.9 days vs. 6.4 +/- 3.7 days, p = 0.026), and lower hospitalization costs (16639.5 +/- 5091.3 CNY vs. 24030.4 +/- 6803.1 CNY, p < 0.001) than the LR group. The ER group had a lower rate of long-term complications than the LR group (p = 0.001) during the follow-up period (84.2 +/- 17.9 months vs. 89.0 +/- 16.8 months, p = 0.207). Conclusions: Our results showed that ER was a more feasible treatment approach than LR when the gastric MP-GIST was located in or near the cardia/pylorus. ER also had several other advantages over LR, such as a shorter procedure time, shorter hospital stay, and lower hospitalization costs.

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