文献类型：期刊文献

英文题名：Treatment with paiteling for cervical high-risk human papillomavirus infection

作者：Tao, Pingping[1];Meng, Xiaohua[2];Chen, Junxia[2];Sun, Aijing[3];Shou, Qinghe[2];Yang, Binlie[1];Zheng, Weiping[2]

机构：[1]Peoples Hosp Shanghai Pudong Dist, Dept Obstet & Gynecol, 490 Chuanhuan South Rd, Shanghai 201299, Peoples R China;[2]Peoples Hosp Shaoxing, Dept Gynaecol, 575 Pingjiang Rd, Shaoxing 312000, Peoples R China;[3]Shaoxing Univ, Dept Pathol, Shaoxing, Peoples R China

年份：2018

卷号：11

期号：5

起止页码：4912

外文期刊名：INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE

收录：SCI-EXPANDED(收录号：WOS:000434031300066)、、WOS

基金：This study was supported by Key Scientific Research Project of Shaoxing City of Zhejiang Province (2011A23017); Subject Leaders Training Program of the Health System in Pudong New Area of Shanghai (PWRd2013-09), and Key Specialized Subject of Cervical Disease Program of Health System in Pudong New Area of Shanghai (PWZz2013-14).

语种：英文

外文关键词：Papillomavirus infection; LEEP; Chinese medicines; paiteling; outcome; clearance rate

外文摘要：Objective: The present study evaluated the efficacy of Paiteling to eliminate Human papillomavirus (HPV) infection from cervix. Method: The patients were divided into loop electrosurgical excision procedure group (LEEP group, n=82) and non-LEEP group (n=239) in light of the cervical intrapithelial neoplasia classification. The two groups were subgrouped to paiteling group and control group by using random number table. All patients underwent thinprep cytologic test (TCT) and HR-HPV test every three months for one year. The negative conversion rate of HR-HPV and the regression rate of cervical lesions were compared between the two subgroups. Results: The negative conversion rate was higher than those in control subgroup at 6-, 9- and 12-month in non-LEEP group and LEEP group with paiteling, respectively. The regression rate of cervical lesions was significantly higher than those in control subgroup at 6-, 9-and 12-month in non-LEEP group with paiteling, respectively, while it did not differ between the two subgroups in LEEP group with paiteling. Conclusion: Paiteling can reverse early Paiteling cervical HR-HPV infection, shorten the duration of HPV infection, promote lesions subsided. To a certain extent, the removal of the residual virus and the disappearance of the disease can be accelerated.