文献类型：期刊文献

中文题名：颅脑损伤患者精神障碍和相关因素分析

英文题名：Risk factors related to mental disorder in patients with craniocerebral injury

作者：徐水琴[1,2];陈三妹[1];张登科[1]

机构：[1]绍兴文理学院护理系,312000;[2]附属医院精神科

年份：2013

卷号：34

期号：5

起止页码：520

中文期刊名：中华流行病学杂志

外文期刊名：Chinese Journal of Epidemiology

收录：MEDLINE(收录号：24016447)、CSTPCD、、北大核心2011、Scopus(收录号：2-s2.0-84928048761)、北大核心、CSCD、PubMed、CSCD2013_2014

基金：教育部人文社会科学研究青年基金（09YJCXLX019）;绍兴市哲学社会科学研究“十二五”规划重点课题（125219）

语种：中文

中文关键词：颅脑损伤;精神障碍;危险因素

外文关键词：Craniocerebral injury; Mental disorder; Risk factors

中文摘要：目的探讨颅脑损伤患者与伴发精神障碍的相关性，并分析其相关因素。方法选取2008年9月至2012年9月颅脑损伤患者342例，统计和分析患者的人口学资料（性别、年龄、文化程度、职业和家庭满意度），并进行头部CT扫描检查和智商、记忆商测试以及SCID-1／P、PDQC、SCICP评估。分析患者一般资料及颅脑损伤性质、程度、部位与发生精神障碍的相关性，采用logistic多因素回归分析独立危险因素。结果342例颅脑损伤患者伴发精神障碍249例，发生率为72．8％。其中抑郁症117例（47．0％），焦虑障碍95例（38．2％），躁狂症27例（10．8％），智能和记忆障碍69例（27．7％）。经相关分析显示颅脑损伤患者的年龄、文化程度、职业和家庭满意度及颅脑损伤性质、程度、部位均与伤后伴发精神障碍相关，logistic多因素回归分析显示患者年龄（0R值〉1．04）、颅脑损伤程度（OR值〉1．28）和颅脑损伤部位（OR值〉1．31）为颅脑损伤患者伴发精神障碍的独立危险因素。结论颅脑损伤伴精神障碍发生率较高，患者年龄、颅脑损伤程度和部位是伴发精神障碍的独立危险因素。

外文摘要：Objective To explore the correlation between mental disorder and craniocerebral injury, and notifying its related risk factors. Methods 342 patients from Sep. 2008 to Sep. 2012 with craniocerebral injury were selected and related clinical data on general their conditions, including sex, age, educational level, satisfaction on careers and relations to family were collected. All the patients received CT-scans to the head, IQ test, MQ test, SCID-1/P, PDQC and SCICP detection. Multivariate logistic regression was used to analyze the general information and cerebral injurious conditions of patients regarding the incidence of mental disorders. Results 249 patients with mental disorder were noticed out of the total 342 patients with craniocerebral injury, with the incidence rate as 72.8% including 117 depression （47.0%）, 95 anxiety disorders （38.2%）, 27 mania （10.8%）, 69 intelligence and memory disorders （27.7%） cases. Data from correlation analysis showed that factors as sex, age, educational level, satisfaction on careers and family of patients as well as type, severity and location of the craniocerebral injuries appeared to have important correlation with mental disorder. Results also showed that the age of patients （OR 〉 1.04）, severity and location of the craniocerebral injuries （OR1 〉 1.28, OR2〉 1.31 ） were independent risk factors （P〈0.05）. Conclusion The age of patients, severity and location of the craniocerebral injuries were independent risk factors for mental disorder in patients with craniocerebral injury.