文献类型：期刊文献

英文题名：Low-to-Moderate-Intensity Resistance Exercise Is More Effective than High-Intensity at Improving Endothelial Function in Adults: A Systematic Review and Meta-Analysis

作者：Zhang, Yong[1];Zhang, Ya-Jun[1];Zhang, Hong-Wei[1];Ye, Wei-Bing[2];Korivi, Mallikarjuna[2]

机构：[1]Shaoxing Univ, Dept Rehabil Med, Shaoxing 312000, Peoples R China;[2]Zhejiang Normal Univ, Coll Phys Educ & Hlth Sci, Jinhua 321004, Zhejiang, Peoples R China

年份：2021

卷号：18

期号：13

外文期刊名：INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH

收录：SSCI(收录号：WOS:000671208700001)、SCI-EXPANDED(收录号：WOS:000671208700001)、、Scopus(收录号：2-s2.0-85108181571)、WOS

基金：This work was funded by the National Social Science Foundation of China (grant number 17BTY008).

语种：英文

外文关键词：endothelial function; resistance exercise; flow-mediated dilatation; meta-analysis

外文摘要：Aerobic exercise has been confirmed to improve endothelial function (EF). However, the effect of resistance exercise (RE) on EF remains controversial. We conducted this systematic review and meta-analysis on randomized controlled trials (RCTs) to determine the effect of RE and its intensities on EF. We searched Web of Science, PubMed/MEDLINE, Scopus, and Wiley Online Library, and included 15 articles (17 trials) for the synthesis. Overall, RE intervention significantly improved flow-mediated dilatation (FMD) in brachial artery (SMD = 0.76; 95% CI: 0.47, 1.05; p < 0.00001), which represents improved EF. Meta-regression showed that the RE intensity was correlated with changes in FMD (Coef. = -0.274, T = -2.18, p = 0.045). We found both intensities of RE improved FMD, but the effect size for the low- to moderate-intensity (30-70%1RM) was bigger (SMD = 1.02; 95% CI: 0.60, 1.43; p < 0.0001) than for the high-intensity (>= 70%1RM; SMD = 0.48; 95% CI: 0.21, 0.74; p = 0.005). We further noticed that RE had a beneficial effect (SMD = 0.61; 95% CI: 0.13, 1.09; p = 0.01) on the brachial artery baseline diameter at rest (BAD(rest)), and the age variable was correlated with the changes in BAD(rest) after RE (Coef. = -0.032, T = -2.33, p = 0.038). Young individuals (<40 years) presented with a bigger effect size for BAD(rest) (SMD = 1.23; 95% CI: 0.30, 2.15; p = 0.009), while middle-aged to elderly (>= 40 years) were not responsive to RE (SMD = 0.07; 95% CI: -0.28, 0.42; p = 0.70). Based on our findings, we conclude that RE intervention can improve the EF, and low- to moderate-intensity is more effective than high-intensity.