文献类型：期刊文献

中文题名：华法林对78例非瓣膜性心房颤动患者抗凝疗效及安全性观察

英文题名：The antithrombotic effects and safety of warfarin in 78 cases of patients with nonvalvular atrial fibrillation

作者：常文秀[1];傅永平[1]

机构：[1]绍兴文理学院附属医院内科

年份：2013

卷号：51

期号：9

起止页码：143

中文期刊名：中国现代医生

外文期刊名：China Modern Doctor

基金：2012年浙江省卫生厅科技项目(2012KYB212)

语种：中文

中文关键词：非瓣膜性心房颤动;华法林;国际标准化比值

外文关键词：Nonvalvular atrial fibrillation; Warfarin; International standardization ratio

中文摘要：目的比较华法林在非瓣膜性心房颤动患者中的抗凝疗效及安全性。方法 2007年11月～2010年9月在我院门诊及住院的非瓣膜性心房颤动患者156例,随机分为华法林组及阿司匹林组各78例。比较两组患者血栓栓塞等终点事件和不良反应发生率。结果华法林组血栓栓塞等终点事件发生率显著低于阿司匹林组(P<0.05),两组不良反应发生率差异无统计学意义(P>0.05)。结论华法林对非瓣膜性心房颤动患者的抗凝疗效优于阿司匹林组。

外文摘要：Objective To explore the antithrombotic effects and safety of warfarin in nonvalvular atrial fibrillation. Methods From November 2007 to September 2010 in our hospital inpatient and outpatient nonvalvular atrial fibrillation patients of 156 cases were randomly divided into two groups, warfarin group and aspirin group,78 cases each. Compared between the two groups were thromboembolism and end events and adverse reaction rate. Results In warfarin group,incidence rate of thromboembolism were significantly lower than aspirin group （P 〈 0.05）, and there was no difference in incidence rate of adverse drug reaction between aspin group and warfarin group （P 〉 0.05）. Conclusion Warfarin is more effective than aspirin for prevention of thromboembolism events in patients with nonvalvular atrial fibrillation.