文献类型：期刊文献

英文题名：Radical Cascade Bicyclization/Aromatization of 1,7-Enynes with 1,3-Dicarbonyl Compounds towards 2,3-Dihydro-1H-cyclopenta[a]naphthalenes

作者：Cai, Tao[1,2];Zhang, Zhebing[1];Li, Peiqin[1];Sun, Tao[1];Chen, Xinyu[1];Ni, Yuqi[1];Chen, Jianhui[1,2];Xu, Huiting[1,2];Xu, Yanfei[1,2];Wu, Chunlei[1,2];Shen, Runpu[1,2];Gao, Yuzhen[3]

机构：[1]Shaoxing Univ, Coll Chem & Chem Engn, Shaoxing 312000, Peoples R China;[2]Zhejiang Engn Res Ctr Fat Soluble Vitamin, Shaoxing 312000, Peoples R China;[3]Chinese Acad Sci, Fujian Inst Res Struct Matter, Key Lab Coal Ethylene Glycol & Its Related Techno, Fuzhou 350002, Fujian, Peoples R China

年份：2021

卷号：363

期号：15

起止页码：3750

外文期刊名：ADVANCED SYNTHESIS & CATALYSIS

收录：SCI-EXPANDED(收录号：WOS:000668853800001)、、WOS、CCR-EXPANDED(收录号：WOS:000668853800001)

基金：We gratefully thank the Zhejiang Provincial Natural Science Foundation of China (No. LQ21B020005), as well as the Public Projects of Zhejiang Province of China (No. LGG19B020002). Gao, Y. also thanks the financial supports from NSFC (Grant No. 21801240).

语种：英文

外文关键词：Silver; Cascade radical cyclization; 1,7-Enyne; 1,3-Dicarbonyl compounds; 2,3-Dihydro-1H-cyclopenta[a]naphthalenes

外文摘要：An Ag-catalyzed radical cascade bicyclization/aromatization of C-linked 1,7-enynes with 1,3-dicarbonyls has been achieved, providing a step- and atom-economy approach for the construction of 2,3-dihydro-1H-cyclopenta[a]naphthalenes, an important structural scaffold existed in biologically active compounds. From this transformation, structurally diverse 2,3-dihydro-1H-cyclopenta[a]naphthalenes were obtained in moderate to good yields with high regioselectivity. Moreover, the further product derivatizations were also exemplified.