文献类型：期刊文献

中文题名：糖尿病足患者溃疡面感染的影响因素及不同敷料的预防效果评价

英文题名：The influencing factors of ulcer surface infection in diabetic foot patients and preventive effect of different dressings

作者：陈魏燕[1];杨贵儿[1];宁荣香[1];曾玉梅[1];钱静莉[1]

机构：[1]绍兴文理学院附属医院糖尿病专科

年份：2019

卷号：29

期号：7

起止页码：1042

中文期刊名：中华医院感染学杂志

外文期刊名：Chinese Journal of Nosocomiology

收录：CSTPCD、、北大核心2017、CSCD_E2019_2020、北大核心、CSCD

基金：绍兴市科技计划基金资助项目(2015B70041)

语种：中文

中文关键词：糖尿病足;感染;敷料;预防

外文关键词：Diabetic foot;Infection;Dressing;Prevention

中文摘要：目的探究糖尿病足患者溃疡面感染的影响因素,评价不同敷料的预防效果,为糖尿病足合并溃疡患者的治疗提供思路。方法选取2015年4月-2017年7月医院收治的148例糖尿病足患者为研究对象,根据随机数表法分成研究组和对照组,每组74例患者,分别采用纳米银抗菌敷料及凡士林敷料,对其相关临床病例资料进行分析,探究感染的影响因素,对比两组患者治疗后感染的发生情况。结果 148例糖尿病足患者,住院期间发生溃疡面感染38例,感染率25.68%;单因素分析表明高龄、合并糖尿病血管并发症、合并视网膜病变、溃疡数目≥3个、合并骨髓炎、合并糖尿病肾病及吸烟史的患者更易发生溃疡面感染(P<0.05);多因素Logistic回归分析结果显示,合并血管并发症、合并视网膜病变、溃疡数目≥3个、合并骨髓炎、合并糖尿病肾病是患者发生溃疡面感染的危险因素(P<0.05);不同敷料分析结果显示研究组溃疡面感染率为20.27%,低于对照组31.08%(P<0.05)。结论糖尿病足部溃疡感染是多种因素共同作用而致,临床应针对高危因素采取针对性的预防措施,降低糖尿病足溃疡感染率,纳米银抗菌敷料可有效预防糖尿病足溃疡感染,值得临床推广应用。

外文摘要：OBJECTIVE To explore the influencing factors of ulcer surface infection in diabetic foot patients, evaluate the preventive effect of different dressings, and provide reference for clinical prevention and treatment. METHODS 148 cases of diabetic foot patients treated in the hospital from Apr. 2015-July. 2017 were selected as the research objects, and rahdomly divided into the research group and the control group, with 74 cases in each group. The two groups were treated respectively using nanometer silver antibacterial dressing and vaseline dressing, and the related clinical data were analyzed. The influencing factors of infection were explored, and the occurrence of infection in patients of the two groups after treatment were compared. RESULTS Among the 148 patients with diabetic foot, 38 cases of ulcer surface infection occurred during hospitalization, and the infection rate was 25.68%, The results of univariate analysis showed that patients with advanced age, diabetic vascular complications,retinopathy, ulcer number greater than or equal to 3 , osteomyelitis, diabetic nephropathy and smoking history were more likely to have ulcer surface infection (P<0.05). Multivariate logistic regression analysis showed that vascular complications, retinopathy, ulcer number greater than or equal to 3, osteomyelitis and diabetic nephropathy were risk factors for ulcer surface infection in patients with diabetic foot. The incidence of ulcer surface infection was 20.27% in the study group, significantly lower than that in the control group which was 31.08%(P<0.05). CONCLUSION Diabetic foot ulcer infection is caused by the combined action of multiple factors. Targeted preventive measures should be taken according to the high-risk factors to reduce the infection rate of diabetic foot ulcer.Nano silver antibacterial dressing can effectively prevent diabetic foot ulcer infection and is worthy of clinical promotion and application.