文献类型：期刊文献

英文题名：NaH-promoted one-pot synthesis of 5-amidoimidazoles from arylamines, carbon disulfide and isocyanides

作者：Luo, Jie[1];Zhang, Yichan[2];Yan, Qiuxia[1];Yang, Guo[1];Zhang, Yaohong[1];Wang, Hai[1]

机构：[1]Shaoxing Univ, Coll Life Sci, Zhejiang Key Lab Alternat Technol Fine Chem Proc, Coll Yuanpei,Coll Chem & Chem Engn, Shaoxing 312000, Zhejiang, Peoples R China;[2]Yancheng Inst Technol, Dept Chem & Chem Engn, Yancheng 224051, Jiangsu, Peoples R China

年份：0

外文期刊名：MOLECULAR DIVERSITY

收录：SCI-EXPANDED(收录号：WOS:000767001000001)、、Scopus(收录号：2-s2.0-85126069959)、WOS

基金：The work was financially supported by the National Innovation and Entrepreneurship Training Program for college students (No. 202010349031) and Natural Science Foundation for colleges and universities in Anhui Province (No. YJS20210138).

语种：英文

外文关键词：5-amidoimidazole; NaH-promoted; Aryamines; Carbon disulfide; Isocyanides

外文摘要：A novel, convenient and efficient protocol to access functionalized 5-amidoimidazoles is developed via one-pot synthesis from readily available materials of arylamines, carbon disulfide and isocyanides. The transformation was realized at room temperature and provided 5-amidoimidazoles in moderate to good yields in the presence of NaH. In addition, control experiments indicated that the process might be achieved via the base-induced cyclization of activated methylene isocyanides with N,N-disubstituted thioureas that produced from the reaction of amines and carbon disulfide.