文献类型：期刊文献

英文题名：One-pot synthesis of sulfonylhydrazones from sulfonyl chloride, hydrazine hydrate and vinyl azide in water

作者：Luo, Mengqiang[1];Wang, Hai[2];Ren, Xiaorong[1];Lu, Ruijuan[1];Qi, Chenze[1];Zhang, Yaohong[1];Shen, Runpu[1]

机构：[1]Shaoxing Univ, Sch Chem & Chem Engn, Zhejiang Key Lab Alternat Technol Fine Chem Proc, Shaoxing 312000, Zhejiang, Peoples R China;[2]Shaoxing Univ, Sch Life Sci, Shaoxing 312000, Zhejiang, Peoples R China

年份：2021

卷号：18

期号：10

起止页码：2713

外文期刊名：JOURNAL OF THE IRANIAN CHEMICAL SOCIETY

收录：SCI-EXPANDED(收录号：WOS:000629856700001)、、Scopus(收录号：2-s2.0-85102556097)、WOS

基金：We gratefully acknowledge the financial support from Zhejiang Provincial Natural Science foundation of China (No. LQ16H090004) and Research Project of Shaoxing University (No. 2017LG1003). We also thank Anna Kerkula for English language editing.

语种：英文

外文关键词：Sulfonylhydrazone; Vinyl azide; Sulfonyl chloride; Water; One pot

外文摘要：A facile and eco-friendly protocol for the synthesis of sulfonylhydrazones from sulfonyl chlorides, hydrazine hydrate and vinyl azides was developed. The unique advantage of this approach is that desired products can be obtained efficiently in water, which meets the requirements of green chemistry and provides good perspectives for the sustainable production of new drug candidate. Also, this reaction proceeded in moderate to good yields with a wide tolerance of functional groups.