文献类型：期刊文献

英文题名：Surgical versus non-operative treatment for lumbar disc herniation: a systematic review and meta-analysis

作者：Chen, Bing-Lin[1];Guo, Jia-Bao[2];Zhang, Hong-Wei[3];Zhang, Ya-Jun[4];Zhu, Yi[5];Zhang, Juan[6];Hu, Hao-Yu[6];Zheng, Yi-Li[6];Wang, Xue-Qiang[6]

机构：[1]Nanjing Univ TCM, Dept Rehabil, Jiangsu Prov Hosp TCM 2, Affiliated Hosp 2, Nanjing, Jiangsu, Peoples R China;[2]Shanghai Univ Sport, Shanghai, Peoples R China;[3]Shaoxing Univ, Shaoxing Rehabil Hosp, Affiliated Hosp, Shaoxing, Peoples R China;[4]Shaoxing Univ, Sports Coll, Shaoxing, Peoples R China;[5]Hainan Prov Nongken Gen Hosp, Haikou, Hainan, Peoples R China;[6]Shanghai Univ Sport, Dept Sport Rehabil, Shanghai 200438, Peoples R China

年份：2018

卷号：32

期号：2

起止页码：146

外文期刊名：CLINICAL REHABILITATION

收录：SCI-EXPANDED(收录号：WOS:000426004700003)、、Scopus(收录号：2-s2.0-85040827457)、WOS

基金：The author(s) disclosed receipt of the following financial support for the research, authorship and/or publication of this article: This study was supported by the National Natural Science Foundation of China (81501956), Shanghai Key Lab of Human Performance (Shanghai University of Sport) (no. 11DZ2261100), Innovation Program of Shanghai Municipal Education Commission (15ZZ084), Shanghai Committee of Science and Technology (14490503800), Shanghai Youth Science and Technology Sail Project (15YF1411400) and Zhejiang Province Education Department Research Program (Y201635345).

语种：英文

外文关键词：Surgical treatment; non-operative treatment; lumbar disc herniation; systematic review; meta-analysis

外文摘要：Objective: To investigate the effects of surgical versus non-operative treatment on the physical function and safety of patients with lumbar disc herniation. Data sources: PubMed, Cochrane Library, Embase, EBSCO, Web of Science, China National Knowledge Infrastructure and Chinese Biomedical Literature Database were searched from initiation to 15 May 2017. Methods: Randomized controlled trials that evaluated surgical versus non-operative treatment for patients with lumbar disc herniation were selected. The primary outcomes were pain and side-effects. Secondary outcomes were function and health-related quality of life. A random effects model was used to calculate the pooled mean difference with 95% confidence interval. Results: A total of 19 articles that involved 2272 participants met the inclusion criteria. Compared with non-operative treatment, surgical treatment was more effective in lowering pain (short term: mean difference=-0.94, 95% confidence interval=-1.87 to -0.00; midterm: mean difference=-1.59, 95% confidence interval=-2.24 to -9.94), improving function (midterm: mean difference=-7.84, 95% confidence interval=-14.00 to -1.68; long term: mean difference=-12.21, 95% confidence interval=-23.90 to -0.52) and quality of life. The 36-item Short-Form Health Survey for physical functions (short term: mean difference=6.25, 95% confidence interval=0.43 to 12.08) and bodily pain (short term: mean difference=5.42, 95% confidence interval=0.40 to 10.45) was also utilized. No significant difference was observed in adverse events (mean difference=0.82, 95% confidence interval=0.28 to 2.38). Conclusion: Low-quality evidence suggested that surgical treatment is more effective than non-operative treatment in improving physical functions; no significant difference was observed in adverse events. No firm recommendation can be made due to instability of the summarized data.