文献类型：期刊文献

英文题名：Accurately Tunable AuNC-ZIF Content Architecture Based on Coordination-Dissociation Mechanism Enables Highly Brightness Dual-Site Fluorescent Biosensor

作者：Chen, Junyang[1]; Wang, Yuqian[1]; Shen, Runpu[2]; Li, Wei[3]; Gao, Sainan[1]; Xiao, Zhikang[4]; Lv, Qiyan[1]; Song, Xiaojie[1]; Xu, Jianzhong[3]; Xu, Gaoxiang[4]; Cui, Huifang[1]; Li, Zhaohui[5]

机构：[1] School of Life Sciences, Zhengzhou University, Henan, Zhengzhou, 450001, China; [2] School of Chemistry and Chemical Engineering, Shaoxing University, Zhejiang, Shaoxing, 312000, China; [3] School of Basic Medical Sciences, Zhengzhou University, Henan, Zhengzhou, 450001, China; [4] Department of Orthopedics, The First Affiliated Hospital of Zhengzhou University, Henan, Zhengzhou, 450052, China; [5] College of Chemistry, Institute of Analytical Chemistry for Life Science, Zhengzhou University, Henan, Zhengzhou, 450001, China

年份：2024

外文期刊名：Advanced Science

收录：EI(收录号：20244917486424)、Scopus(收录号：2-s2.0-85211105744)

语种：英文

外文关键词：Gluing - Hard facing - Hydrogels - Layered semiconductors - Nanoclay - Nanoclusters - Nanocrystals

外文摘要：The quantum yield and fluorescence intensity of gold nanocluster (AuNC) nanocarriers are critical parameters for developing ultrasensitive biosensors. In this study, AuNCs-zeolitic-imidazolate-framework (Au-ZIF) nanocomposites are systematically constructed by impregnating AuNCs onto the ZIF-8 surface through a coordination-dissociation mechanism, resulting in a dual-site fluorescence-loaded structure. In this configuration, AuNCs are anchored to the external surface while the integrity of the inner cavity remains intact. The surface of ZIF-8 induces a confinement effect on the configuration and electrons of AuNCs, significantly enhancing luminescence (18-fold increase). The quantum yield of AuNCs exhibits an increase of more than 13-fold, from 2.80% to 38.1%. This approach demonstrates broad applicability and maintains strong fluorescence across different ZIFs. Additionally, a novel nanocomposite, Au-ZIF@carbon-dots (CDs), is synthesized by encapsulating CDs into the inner cavity of Au-ZIF. A ratiometric fluorescence detection platform is subsequently developed and incorporated into hydrogels for the quantitative detection of the pesticide triazophos. By employing an image-processing algorithm, quantitative detection is achieved with a detection limit of 0.07?ng mL?1. The findings provide crucial insights into the relationship between the assembly and performance of AuNCs and ZIFs, offering guidance for designing ultrasensitive multifunctional biosensors applicable in the field of biosensing. ? 2024 The Author(s). Advanced Science published by Wiley-VCH GmbH.