文献类型：期刊文献

中文题名：他汀类药物治疗扩张型心肌病心力衰竭的临床依据和可能机制的研究进展

英文题名：Clinical Evidences and Possible Mechanisms of Statins in Treatment of Heart Failure due to Dilated Cardiomyopathy:Progress in Research

作者：许富康[1];郭航远[2];邢杨波[2]

机构：[1]温州医学院研究生院,浙江省温州市325000;[2]绍兴文理学院附属第一医院心内科

年份：2008

卷号：11

期号：4

起止页码：320

中文期刊名：中国全科医学

外文期刊名：Chinese General Practice

收录：CSTPCD、、Scopus、CSCD_E2011_2012、CSCD

语种：中文

中文关键词：他汀类;心肌病,扩张型;心力衰竭

外文关键词：Statin; Cardiomyopathy, dilated; Heart failure

中文摘要：目的他汀类药物具有肯定的降脂作用,已作为冠状动脉粥样硬化性心脏病的二级预防用药。大量研究显示,他汀类药物还具有降脂之外的抑制炎症反应、抗心室重塑、改善神经体液调节、抗心律失常、改善血管内皮功能、抗氧化等作用。本文对他汀类药物治疗扩张型心肌病心力衰竭的临床依据和可能机制做一综述。

外文摘要：Statins plays a role in reducing blood LDL cholesterol, acting as a second - level prevention drug for coronary artery disease. Many studies have shown that statins has many other contributions to anti - inflammation, anti - ventricular remodeling, anti - arrhythmia, anti - oxidat and improvement of neurohumoral regulation and of endothelial function besides their effect on blood fat decrease. Heart function and sympotoms are improved when statins is used in patients with heart failure due to dilated cardiomyopathy.