详细信息
抗抑郁辅助治疗慢性前列腺炎的疗效分析 被引量:1
Efficacy analysis of antidepressant-assisted treatment for chronic prostatitis
文献类型:期刊文献
中文题名:抗抑郁辅助治疗慢性前列腺炎的疗效分析
英文题名:Efficacy analysis of antidepressant-assisted treatment for chronic prostatitis
作者:刘铸[1]
机构:[1]绍兴文理学院附属医院泌尿外科,浙江省绍兴312000
年份:2013
期号:8
起止页码:1157
中文期刊名:中国基层医药
外文期刊名:Chinese Journal of Primary Medicine and Pharmacy
语种:中文
中文关键词:前列腺炎;帕罗西汀
外文关键词:Prostatitis ; Paroxetine
中文摘要:目的探讨抗抑郁辅助治疗慢性前列腺炎(cP)的疗效,寻找有效治疗cP的临床疗法。方法将88例CP患者随机分为两组,对照组41例采用抗菌药物莫西沙星治疗,治疗组47例在莫西沙星治疗的同时,采用帕罗西汀辅助治疗。评价并比较治疗前后两组临床症状与生活质量(QOL)、Zung抑郁量表评分。结果治疗4周后,治疗组排尿不畅不尽、尿频尿急、会阴部不适等症状显著改善,与对照组差异有统计学意义(Х^2=23.563、18.348、15.874,均P〈0.05)。治疗后治疗组QOL、Zung抑郁量表评分较治疗前、对照组治疗后显著下降(t=0.554、0.615、0.382、0.336,均P〈0.05)。结论抗抑郁辅助治疗在改善CP患者的精神症状的同时,可有效提高抗菌药物治疗CP的临床疗效。
外文摘要:Objective To explore the effect of antidepressant adjuvant treatment for chronic prostatitis (CP) ,and to find an effective treatment for the clinical therapy of CP. Methods 88 patients with CP were randomly divided into two groups ,the control group 41 patients were treated with the antibacterials moxifloxacin, the treatment group 47 patients were treated with the moxifloxacin treatment and paroxetine adjuvant therapy. The clinical symptoms, life quality (QOL) and Zung depression scale score of the two groups were evaluated and compared. Results After four weeks of treatment, voiding difficulty endless, urinary urgency, perineal discomfort symptoms of the treatment group were improved significantly compared with the control group ( Х^2 = 23. 563,18. 348,15. 874, all P 〈 0.05 ). After four weeks of treatment, QOL, Zung depression scale scores the treatment group were more significant decline than before treatment and the control group after treatment (t = 0.554,0. 615,0. 382,0. 336, all P 〈 0.05 ). Conclusion Antidepressant adjuvant therapy improves the psychiatric symptoms of CP patients,which can effectively improve the clinical efficacy of antibiotic therapy of CP.
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