文献类型：期刊文献

英文题名：Global Geographic Patterns of Soil Microbial Degradation Potential for Polycyclic Aromatic Hydrocarbons

作者：Gao, Mingyu[1];Zhang, Qi[2];Chen, Bingfeng[1];Lei, Chaotang[1];Xia, Qingshan[1];Sun, Liwei[1];Li, Tao[3,4];Zhou, Ning-Yi[3,4];Lu, Tao[1];Qian, Haifeng[2]

机构：[1]Zhejiang Univ Technol, Coll Environm, Hangzhou 310032, Peoples R China;[2]Shaoxing Univ, Inst Adv Study, Shaoxing 312000, Peoples R China;[3]Shanghai Jiao Tong Univ, State Key Lab Microbial Metab, Shanghai 200240, Peoples R China;[4]Shanghai Jiao Tong Univ, Sch Life Sci & Biotechnol, Shanghai 200240, Peoples R China

年份：2025

卷号：59

期号：15

起止页码：7550

外文期刊名：ENVIRONMENTAL SCIENCE & TECHNOLOGY

收录：SCI-EXPANDED(收录号：WOS:001466607200001)、、EI(收录号：20251618259234)、Scopus(收录号：2-s2.0-105003136919)、WOS

基金：This work was financially supported by the National Key Research and Development Program of China (2021YFA0909500), the Zhejiang Provincial Natural Science Foundation of China (LZ23B070001), the National Natural Science Foundation of China (42377107, 42307158, and 22176176), the Open Funding Project of the State Key Laboratory of Microbial Metabolism (MMLKF23-03), and the project of the Key scientific and technological Program of Hangzhou (2023SZD0058).

语种：英文

外文关键词：polycyclic aromatic hydrocarbons; hidden Markov model; degradation potential; virulence factors

外文摘要：Polycyclic aromatic hydrocarbons (PAHs) are toxic and persistent pollutants that are widely distributed in the environment. PAHs are toxic to microorganisms and pose ecological risks. Bacteria encode enzymes for PAH degradation through specific genes, thereby mitigating PAH pollution. However, due to PAHs' complexity, information on the global degradation potential, diversity, and associated risks of PAH-degrading microbes in soils is lacking. In this study, we analyzed 121 PAH-degrading genes and selected 33 as marker genes to predict the degradation potential within the soil microbiome. By constructing a Hidden Markov Model, we identified 4990 species carrying PAH-degrading genes in 40,039 soil metagenomic assembly genomes, with Burkholderiaceae and Stellaceae emerging as high-potential degraders. We demonstrated that the candidate PAH degraders predominantly emerged in artificial soil and farmland, with significantly fewer present in extreme environments, driven by factors such as average annual rainfall, organic carbon, and human modification of terrestrial systems. Furthermore, we comprehensively quantified the potential risks of each potential host in future practical applications using three indicators (antibiotic resistance genes, virulence factors, and pathogenic bacteria). We found that the degrader Stellaceae has significant application prospects. Our research will help determine the biosynthetic potential of PAH-degrading enzymes globally and further identify potential PAH-degrading bacteria at lower risk.